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WAY 121520

Known as: 1H-Indole-3-acetic acid, 1-((4-chlorophenyl)methyl)-2-methyl-5-(2-quinolinylmethoxy)-, WAY-121,520, WAY-121520 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

IndomethacinQuinolines
acemetacinanalogs & derivatives

Papers overview

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2005
2005
Pharmacological characterization of WAY-121,520: A potent anti-inflammatory indomethacin-based inhibitor of 5-lipoxygenase (5-LO)/phospholipase A2 (PLA2)
WAY-121,520 inhibited human synovial fluid PLA2 (HSF-PLA2) (IC50=4 μM) using arachidonic acid-labeledE. coli as substrate… 
2005
2005
Structure-activity relationships leading to WAY-121,520, a tris aryl-type, indomethacin-based, phospholipase A2 (PLA2)/leukotriene biosynthesis inhibitor
We were intrigued by reports of the inhibition of phospholipase A2 (PLA2) by indomethacin. In order to increase the potency of… 
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