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Von Hippel-Lindau Tumor Suppressor Protein

Known as: VHL Tumor Suppressor Protein, Von Hippel Lindau Tumor Suppressor Protein, Von Hippel-Lindau Tumor Suppressor Protein [Chemical/Ingredient] 
A ubiquitin-protein ligase that mediates OXYGEN-dependent polyubiquitination of HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. It is inactivated in VON… 
National Institutes of Health

Papers overview

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2018
2018
Hypoxia-inducible factor 1 (HIF-1) plays an essential role in the regulation of hypoxia in humans. This regulation is mediated by… 
2016
2016
  • P. Heir, M. Ohh
  • Methods in molecular biology
  • 2016
  • Corpus ID: 5679063
Oxygen-dependent hydroxylation of critical proline residues, catalyzed by prolyl hydroxylase (PHD1-3) enzymes, is a crucial… 
2015
2015
Our previous study suggested that microtubule network alteration affects the process of glycolysis in cardiomyocytes (CMs) via… 
2012
2012
The von Hippel‐Lindau tumor suppressor protein (pVHL) has an essential role in the regulation of the hypoxia response pathway in… 
2008
2008
Targeting the oxygen-sensing mechanisms of the hypoxiainducible factor (HIF) pathway provides pharmacological ways of… 
Review
2007
Review
2007
  • W. Kaelin
  • Methods in enzymology
  • 2007
  • Corpus ID: 23003846
2006
2006
Idiopathic erythrocytosis (IE) is a rare condition in which there is an increase inred cell mass and hematocrit. As it is… 
Highly Cited
1999
Highly Cited
1999
The von Hippel-Lindau tumor suppressor protein pVHL assembles with cullin-2 (hCUL-2) and elongin B/C forming a protein complex…