Von Hippel-Lindau Tumor Suppressor Protein

Known as: VHL Tumor Suppressor Protein, Von Hippel Lindau Tumor Suppressor Protein, Von Hippel-Lindau Tumor Suppressor Protein [Chemical/Ingredient] 
A ubiquitin-protein ligase that mediates OXYGEN-dependent polyubiquitination of HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. It is inactivated in VON… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2017
012320022017

Papers overview

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2017
2017
BACKGROUND Hypoxia-inducible factor 2 alpha (HIF2α), prolyl hydroxylase domain protein 2 (PHD2), and the von Hippel Lindau tumor… (More)
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2010
2010
Inactivation of the von Hippel-Lindau tumor suppressor protein (pVHL) causes the most common form of kidney cancer. pVHL is part… (More)
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2008
2008
Targeting the oxygen-sensing mechanisms of the hypoxiainducible factor (HIF) pathway provides pharmacological ways of… (More)
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Review
2007
Review
2007
Inactivation of the von Hippel-Lindau (VHL) tumor suppressor has been linked to a variety of tumors, including clear cell renal… (More)
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2006
2006
Idiopathic erythrocytosis (IE) is a rare condition in which there is an increase in red cell mass and hematocrit. As it is… (More)
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2006
2006
The tumor suppressor VHL (von Hippel-Lindau protein) serves as a negative regulator of hypoxia-inducible factor-alpha subunits… (More)
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2006
2006
The von Hippel–Lindau tumor suppressor protein (pVHL) suppresses tumor formation by binding the α subunits of hypoxia-inducible… (More)
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2002
2002
Von Hippel-Lindau (VHL) tumor suppressor protein is expressed in neurons of the central nervous system and plays an important… (More)
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