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Von Hippel-Lindau Tumor Suppressor Protein

Known as: VHL Tumor Suppressor Protein, Von Hippel Lindau Tumor Suppressor Protein, Von Hippel-Lindau Tumor Suppressor Protein [Chemical/Ingredient] 
A ubiquitin-protein ligase that mediates OXYGEN-dependent polyubiquitination of HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. It is inactivated in VON… Expand
National Institutes of Health

Papers overview

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2018
2018
Hypoxia-inducible factor 1 (HIF-1) plays an essential role in the regulation of hypoxia in humans. This regulation is mediated by… Expand
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2017
2017
BACKGROUND Hypoxia-inducible factor 2 alpha (HIF2α), prolyl hydroxylase domain protein 2 (PHD2), and the von Hippel Lindau tumor… Expand
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2016
2016
Oxygen-dependent hydroxylation of critical proline residues, catalyzed by prolyl hydroxylase (PHD1-3) enzymes, is a crucial… Expand
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2015
2015
Our previous study suggested that microtubule network alteration affects the process of glycolysis in cardiomyocytes (CMs) via… Expand
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2012
2012
The von Hippel-Lindau tumor suppressor protein (pVHL) has an essential role in the regulation of the hypoxia response pathway in… Expand
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2008
2008
Targeting the oxygen-sensing mechanisms of the hypoxiainducible factor (HIF) pathway provides pharmacological ways of… Expand
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Review
2007
Review
2007
Inactivation of the von Hippel-Lindau (VHL) tumor suppressor has been linked to a variety of tumors, including clear cell renal… Expand
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2006
2006
Idiopathic erythrocytosis (IE) is a rare condition in which there is an increase inred cell mass and hematocrit. As it is… Expand
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1999
1999
The von Hippel-Lindau tumor suppressor protein pVHL assembles with cullin-2 (hCUL-2) and elongin B/C forming a protein complex… Expand
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