Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Von Hippel-Lindau Syndrome

Known as: Angiomatoses, Familial Cerebello-Retinal, Lindau Disease, von-hippel lindau disease 
An inherited familial cancer syndrome which is characterized by development of capillary hemangioblastomas of the central nervous system and retina… Expand
National Institutes of Health

Related topics

Related topics

38 relations
Adenocarcinoma of ampulla of VaterAutosomal dominant inheritanceCentral Nervous System HemangioblastomaCerebellar hemangioblastoma
Expand

Broader (4)

Brain NeoplasmsEye NeoplasmsHereditary DiseasesSyndrome

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Hypoxia, angiogenesis, and metabolism in the hereditary kidney cancers
The field of hereditary kidney cancer has begun to mature following the identification of several germline syndromes that define… Expand
  • figure 1
  • figure 2
  • figure 3
Review
2019
Review
2019
Micromanaging aerobic respiration and glycolysis in cancer cells
Background Cancer cells possess a common metabolic phenotype, rewiring their metabolic pathways from mitochondrial oxidative… Expand
  • figure 1
  • table 1
  • table 2
  • table 2
  • figure 2
Review
2018
Review
2018
VHL and Hypoxia Signaling: Beyond HIF in Cancer
Von Hippel-Lindau (VHL) is an important tumor suppressor that is lost in the majority of clear cell carcinoma of renal cancer… Expand
  • figure 1
Review
2017
Review
2017
A Review of Von Hippel-Lindau Syndrome
Von Hippel-Lindau syndrome (VHL) is a familial neoplastic condition seen in approximately 1 in 36,000 live births. It is caused… Expand
  • table 1
  • table 2
  • table 3
  • figure 1
  • figure 2
Highly Cited
2000
Highly Cited
2000
Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel–Lindau protein
von Hippel–Lindau (VHL) disease is a hereditary cancer syndrome that is characterized by the development of multiple vascular… Expand
  • figure 2
  • figure 1
  • figure 4
  • figure 3
  • figure 6
Highly Cited
2000
Highly Cited
2000
Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein*
The von Hippel-Lindau tumor suppressor protein (pVHL) has emerged as a key factor in cellular responses to oxygen availability… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
1999
Highly Cited
1999
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
Hypoxia-inducible factor-1 (HIF-1) has a key role in cellular responses to hypoxia, including the regulation of genes involved in… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
1995
Highly Cited
1995
Tumour suppression by the human von Hippel-Lindau gene product
A partial cDNA sequence for the gene linked to the von Hippel–Lindau (VHL) syndrome was reported in 1993. Mutation or loss of… Expand
Highly Cited
1994
Highly Cited
1994
Mutations of the VHL tumour suppressor gene in renal carcinoma
Multiple, bilateral renal carcinomas are a frequent occurrence in von Hippel–Lindau (VHL) disease. To elucidate the aetiological… Expand
Highly Cited
1993
Highly Cited
1993
Identification of the von Hippel-Lindau disease tumor suppressor gene.
A gene discovered by positional cloning has been identified as the von Hippel-Lindau (VHL) disease tumor suppressor gene. A… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE