Voltage-Dependent Anion Channels

Known as: VDAC Proteins, Mitochondrial Porin, Anion Channels, Voltage-Dependent 
The Voltage-Dependent Anion Channel (VDAC) is a small, abundant pore-forming eukaryotic protein in the outer mitochondrial membrane thought to form… (More)
National Institutes of Health

Related topics

Related topics

13 relations
In BloodMitochondrial Membrane, OuterProcess of secretionVDAC1 wt Allele
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VDAC DeficiencyVDAC3 protein, humanporin protein, Drosophila

Papers overview

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Highly Cited
2012
Highly Cited
2012
Voltage-dependent anion channels (VDACs) recruit Parkin to defective mitochondria to promote mitochondrial autophagy.
BACKGROUND Parkin is recruited to defective mitochondria to promote degradation by an autophagy mechanism (mitophagy). RESULTS… (More)
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Highly Cited
2008
Highly Cited
2008
Structure of the human voltage-dependent anion channel.
The voltage-dependent anion channel (VDAC), also known as mitochondrial porin, is the most abundant protein in the mitochondrial… (More)
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Highly Cited
2008
Highly Cited
2008
Tubulin binding blocks mitochondrial voltage-dependent anion channel and regulates respiration.
Regulation of mitochondrial outer membrane (MOM) permeability has dual importance: in normal metabolite and energy exchange… (More)
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Highly Cited
2007
Highly Cited
2007
Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death
Mitochondria are critically involved in necrotic cell death induced by Ca2+ overload, hypoxia and oxidative damage. The… (More)
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Highly Cited
2007
Highly Cited
2007
RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels
Therapeutics that discriminate between the genetic makeup of normal cells and tumour cells are valuable for treating and… (More)
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Review
2006
Review
2006
Voltage-dependent anion channel (VDAC) as mitochondrial governator--thinking outside the box.
Despite a detailed understanding of their metabolism, mitochondria often behave anomalously. In particular, global suppression of… (More)
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Highly Cited
2005
Highly Cited
2005
The voltage-dependent anion channel-1 modulates apoptotic cell death
The role of the voltage-dependent anion channel (VDAC) in cell death was investigated using the expression of native and mutated… (More)
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Highly Cited
2003
Highly Cited
2003
Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol.
Several reactions in biological systems contribute to maintain the steady-state concentrations of superoxide anion (O(2)*-) and… (More)
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Review
2002
Review
2002
The voltage-dependent anion channel: an essential player in apoptosis.
The increase of outer mitochondrial membrane permeability is a central event in apoptotic cell death, since it releases several… (More)
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Highly Cited
2002
Highly Cited
2002
Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria
Although the physiological relevance of mitochondrial Ca2+ homeostasis is widely accepted, no information is yet available on the… (More)
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