Vitamin D3 24-Hydroxylase

Known as: 25-Hydroxycholecalciferol-24-Hydroxylase, D3 24-Hydroxylase, 1,25-Dihydroxyvitamin, Vitamin D 24 Hydroxylase 
A cytochrome P-450 enzyme that has specificity for CHOLECALCIFEROL (Vitamin D3). It hydroxylates the molecule at carbon position 24.
National Institutes of Health

Papers overview

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Review
2012
Review
2012
The hormonal metabolite of vitamin D, 1α,25-dihydroxyvitamin D3 (1,25D), initiates biological responses via binding to the… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Vitamin D is crucial for maintenance of musculoskeletal health, and might also have a role in extraskeletal tissues… (More)
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Highly Cited
2009
Highly Cited
2009
Plasma concentrations of biologically active vitamin D (1,25-(OH)(2)D) are tightly controlled via feedback regulation of renal… (More)
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Review
2008
Review
2008
Although researchers first identified the fat-soluble vitamin cholecalciferol almost a century ago and studies have now largely… (More)
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Review
2005
Review
2005
The vitamin D3 25-hydroxylase (CYP27A1), 25-hydroxyvitamin D3 1alpha-hydroxylase (CYP27B1) and 1alpha,25-dihydroxyvitamin D3 24… (More)
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Highly Cited
2005
Highly Cited
2005
The prevalence of multiple sclerosis (MS) increases significantly with decreasing UV B light exposure, possibly reflecting a… (More)
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Highly Cited
2003
Highly Cited
2003
The conversion of vitamin D into an active ligand for the vitamin D receptor requires 25-hydroxylation in the liver and 1alpha… (More)
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Highly Cited
1999
Highly Cited
1999
Because 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) is known to activate the biosynthesis of numerous proteins in various tissues… (More)
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Highly Cited
1985
Highly Cited
1985
An evaluation of surgically obtained skin (age range, 8-92 yr) revealed that there is an age-dependent decrease in the epidermal… (More)
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Highly Cited
1985
Highly Cited
1985
We investigated the 1 alpha-hydroxylation of vitamin D3 sterols by cultured pulmonary alveolar macrophages (PAM) from patients… (More)
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