Vinca

Known as: Periwinkle, Periwinkles 
A plant genus of the family Aponcynaceae.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1951-2018
05010019512017

Papers overview

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Highly Cited
2008
Highly Cited
2008
PURPOSE Several recent trials have shown a significant overall survival (OS) benefit from postoperative cisplatin-based… (More)
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2007
2007
We recently developed a new group of folate-conjugated Vinca alkaloids, one of which, EC145, emerged as a candidate for clinical… (More)
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Highly Cited
2001
Highly Cited
2001
Vinca alkaloids are used extensively in the treatment of childhood acute lymphoblastic leukemia (ALL) and despite their… (More)
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2001
2001
The two second-generation Vinca alkaloids, vinorelbine and vinflunine, affect microtubule dynamics very differently from… (More)
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Highly Cited
1993
Highly Cited
1993
We have investigated the blood flow modifying effects of the vinca alkaloids, vincristine and vinblastine in the murine carcinoma… (More)
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Highly Cited
1991
Highly Cited
1991
We have used a structure-activity approach to investigate whether the Vinca alkaloids inhibit cell proliferation primarily by… (More)
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Highly Cited
1991
Highly Cited
1991
Data generated in the new National Cancer Institute drug evaluation program, which is based on inhibition of cell growth in 60… (More)
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1991
1991
Oral administration of water fraction of alcoholic extract of leaves of Vinca rosea (fam. apocynaeceae) led to marked lowering of… (More)
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Highly Cited
1988
Highly Cited
1988
Multidrug resistance (MDR), typified by resistance to Vinca alkaloids and anthracyclines, is a well characterized experimental… (More)
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Highly Cited
1979
Highly Cited
1979
Starting with an established line of human leukemic lympho blasts (CCRF-CEM), we have developed sublines with varying degrees of… (More)
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