Venlafaxine hydrochloride

Known as: Cyclohexanol, 1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)-, hydrochloride, venlafaxine hcl, hcl venlafaxine 
A synthetic ethyl-cyclohexanol derivative used for the treatment of depression, Venlafaxine Hydrochloride is metabolized to O-desmethylvenlafaxine… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
CONTEXT Some meta-analyses suggest that efficacy of antidepressants for major depression is overstated and limited to severe… (More)
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Highly Cited
2012
Highly Cited
2012
CONTEXT The US Food and Drug Administration issued a black box warning for antidepressants and suicidal thoughts and behavior in… (More)
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2012
2012
In order to improve the bioavailability of the antidepressant drug, venlafaxine hydrochloride, in situ mucoadhesive… (More)
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Highly Cited
2008
Highly Cited
2008
CONTEXT Selective serotonin reuptake inhibitors have been reported to increase the risk of upper gastrointestinal tract bleeding… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE To examine the efficacy of extended-release venlafaxine for the treatment of postmenopausal hot flushes. METHODS… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Approximately 30 000 people die annually by suicide in the United States. Although 60% of suicides occur during a mood… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Functional brain imaging studies in major depression have suggested abnormalities of areas, including the frontal… (More)
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Highly Cited
1999
Highly Cited
1999
According to in-vitro studies with microsomes from human livers and from yeast expression systems with high CYP2D6 activity, the… (More)
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Highly Cited
1998
Highly Cited
1998
PURPOSE Hot flashes can be a prominent clinical problem for breast cancer survivors and men who undergo androgen-deprivation… (More)
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1996
1996
Venlafaxine hydrochloride (Effexor) is a structurally novel antidepressant that inhibits reuptake of 5-hydroxytryptamine and… (More)
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