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Vatalanib Succinate

Known as: 1-[4-Chloroanilino]-4-[4-pyridylmethyl]phthalazine Succinate, Butanedioic Acid, Compd. with N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine (1:1) 
The succinate salt of vatalanib, an anilinophthalazine derivative, with antineoplastic activity. Vatalanib binds to and inhibits the protein kinase… Expand
National Institutes of Health

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2015
2015
Cancer microenvironment is characterized by significantly lower oxygen concentration. This hypoxic condition is known to reduce… Expand
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2014
2014
Leiomyosarcomas remain challenging tumors to manage and novel therapy strategies besides radiation and conventional chemotherapy… Expand
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2011
2011
Objective To optimize the synthesis of vatalanib succinate.Methods Vatalanib succinate was synthesized by condensing 2H-bezofuran… Expand
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2009
2009
Microcrystalline cellulose (MCC) is a well-established pelletisation aid. However, MCC pellets generally do not disintegrate… Expand
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2009
2009
The major aim of this study was to identify an efficient tool to adjust drug release patterns from aqueous and organic… Expand
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2008
2008
A series of novel substituted 1,2,3-benzotriazines based on the structures of vatalanib succinate (PTK787) and vandetanib (ZD6474… Expand
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2008
2008
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… Expand
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2008
2008
Aim To improve the synthetic procedure of vatalanib succinate(PTK787).Methods Starting from phthalide and pyridine-4-carbaldehyde… Expand
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2003
2003
Gateways to clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… Expand
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