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Vaccine Design

Determining the antigens (whole virus, parts or crossreacting) to be incorporated in a vaccine
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Control of HIV-1 replication in vitro by vaccine-induced human CD8+ T cells through conserved subdominant Pol epitopes
Review
2012
Review
2012
The changing face of HIV vaccine research
While there has been remarkable progress in understanding the biology of HIV‐1 and its recognition by the human immune system, we… 
Review
2007
Review
2007
Prospects of HIV Env modification as an approach to HIV vaccine design.
So far, all efforts to engineer immunogens that would elicit broadly reactive anti-HIV neutralizing antibody responses have not… 
2006
2006
Amino acid mutations of the infectious clone from Chinese EIAV attenuated vaccine resulted in reversion of virulence.
Review
2004
Review
2004
Neutralizing antibody responses to HIV: role in protective immunity and challenges for vaccine design
AIDS continues to be a major health problem throughout the world with a high degree of mortality and morbidity. Therefore, there… 
Review
2003
Review
2003
Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design.
Antibodies link antigen and immunological effector systems through the use of highly flexible linkers that connect the… 
Highly Cited
2000
Highly Cited
2000
Induction of Protective Immunity against Chlamydia trachomatis Genital Infection by a Vaccine Based on Major Outer Membrane Protein–Lipophilic Immune Response-Stimulating Complexes
ABSTRACT The significance of delivery systems in modern vaccine design strategies is underscored by the fact that a promising… 
1999
1999
Rational Live Oral Carrier Vaccine Design by Mutating Virulence-Associated Genes of Yersinia enterocolitica
ABSTRACT Three different Yersinia enterocolitica serotype O8 strains harboring mutations in virulence-associated genes coding… 
Highly Cited
1990
Highly Cited
1990
Polarity of immunogens: implications for vaccine design
Peptide constructs have been engineered consisting of amino acid sequence determinant recognized by T cells (TD) co‐linearly… 
1985
1985
Bluetongue vaccine: cells and/or antibodies.
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