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VMP1 gene

Known as: TANGO5, TMEM49, EPG3 
 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease
Epigenetic alterations may provide important insights into gene-environment interaction in inflammatory bowel disease (IBD). Here… Expand
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2014
2014
Vmp1 regulates PtdIns3P signaling during autophagosome formation in Dictyostelium discoideum.
Generation and turnover of phosphatidylinositol 3-phosphate (PtdIns3P) signaling is essential for autophagosome formation and… Expand
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2013
2013
VMP1 is a new player in the regulation of the autophagy-specific phosphatidylinositol 3-kinase complex activation.
We have elucidated a novel mechanism through which the autophagy-specific class III phosphatidylinositol 3-kinase (PtdIns3K… Expand
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2012
2012
A novel source for miR-21 expression through the alternative polyadenylation of VMP1 gene transcripts
miR-21 is the most commonly over-expressed microRNA (miRNA) in cancer and a proven oncogene. Hsa-miR-21 is located on chromosome… Expand
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Highly Cited
2011
Highly Cited
2011
p62 targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding
Autophagy is an intracellular degradation process by which cytoplasmic contents are degraded in the lysosome. In addition to… Expand
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Highly Cited
2010
Highly Cited
2010
Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins.
Autophagy is an intracellular degradation process, through which cytosolic materials are delivered to the lysosome.Despite recent… Expand
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2010
2010
Autophagy dysfunction and ubiquitin-positive protein aggregates in Dictyostelium cells lacking Vmp1.
Ubiquitin-positive protein aggregates are a hallmark of many degenerative diseases. Their presence can be induced by dysfunction… Expand
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Highly Cited
2007
Highly Cited
2007
The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells.
Autophagy is a degradation process of cytoplasmic cellular constituents, which serves as a survival mechanism in starving cells… Expand
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2003
2003
VMP1 Expression Correlates with Acinar Cell Cytoplasmic Vacuolization in Arginine-Induced Acute Pancreatitis
Background: Recently, we described the cloning of VMP1 (vacuole membrane protein 1). In vitro expression of VMP1 promotes… Expand
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2001
2001
Tongue-to-palate contact patterns and variability of four English consonants in an /i/ vowel environment
Minimal data exist describing tongue-to-palate contact patterns and their variability in normal speakers of English. Consequently… Expand
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