VHL protein, human

Known as: von Hippel-Lindau syndrome protein, human, pVHL, von Hippel Lindau Tumor Supressor Protein 
Von Hippel-Lindau disease tumor suppressor (213 aa, ~24 kDa) is encoded by the human VHL gene. This protein plays a role in protein ubiquitination… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Error-free mitosis depends on fidelity-monitoring checkpoint systems that ensure correct temporal and spatial coordination of… (More)
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Highly Cited
2008
Highly Cited
2008
von Hippel-Lindau (VHL) tumor suppressor loss results in hypoxia-inducible factor alpha (HIF-alpha) stabilization and occurs in… (More)
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Review
2004
Review
2004
Germline inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene causes the von Hippel-Lindau hereditary cancer… (More)
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Highly Cited
2003
Highly Cited
2003
Organ-specific metastasis is governed, in part, by interactions between chemokine receptors on cancer cells and matching… (More)
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Highly Cited
2001
Highly Cited
2001
Hypoxia-inducible factor-1alpha (HIF-1alpha) is a global transcriptional regulator of the hypoxic response. Under normoxic… (More)
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Highly Cited
2001
Highly Cited
2001
von Hippel-Lindau (VHL) disease is a hereditary cancer syndrome caused by germ line mutation of the von Hippel-Lindau tumor… (More)
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Highly Cited
2001
Highly Cited
2001
Hypoxia-inducible factor (HIF) is a transcriptional complex that plays a central role in the regulation of gene expression by… (More)
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Highly Cited
2000
Highly Cited
2000
von Hippel–Lindau (VHL) disease is a hereditary cancer syndrome that is characterized by the development of multiple vascular… (More)
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Highly Cited
2000
Highly Cited
2000
The transcriptional complex hypoxia-inducible factor-1 (HIF-1) has emerged as an important mediator of gene expression patterns… (More)
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Highly Cited
1999
Highly Cited
1999
Hypoxia-inducible factor-1 (HIF-1) has a key role in cellular responses to hypoxia, including the regulation of genes involved in… (More)
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