VAD Regimen (Vincristine-Adriamycin-Dexamethasone)

Known as: VAD Regimen, Vincristine-Adriamycin-Dexamethasone Regimen 
A regimen consisting of vincristine, doxorubicin and dexamethasone used as induction treatment for multiple myeloma.
National Institutes of Health

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Highly Cited
2006
Highly Cited
2006
Macrophage cell death plays a role in many physiological and pathophysiological conditions. Previous work has shown that… (More)
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Highly Cited
2004
Highly Cited
2004
Increasing evidence suggests that lysosomal proteases are actively involved in apoptosis. Using HeLa cells as the model system… (More)
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Highly Cited
2003
Highly Cited
2003
The P2X7 ATP receptor mediates the cytotoxic effect of extracellular ATP. P2X7-dependent cell death is heralded by dramatic… (More)
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Highly Cited
2002
Highly Cited
2002
The role of maintenance therapy in multiple myeloma is controversial. Recent studies have shown an improvement in both… (More)
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Highly Cited
2001
Highly Cited
2001
Sensitivity of tumor cells to anticancer therapy depends on the ability of the drug to induce apoptosis. However, multiple… (More)
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Highly Cited
2001
Highly Cited
2001
Bisphosphonate inhibition of bone resorption was proposed to be due to osteoclast apoptosis. We tested this hypothesis for both… (More)
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Highly Cited
1999
Highly Cited
1999
To evaluate the role of ceramide (Cer) in apoptosis signaling, we examined Cer formation induced by CD95, etoposide, or gamma… (More)
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Highly Cited
1998
Highly Cited
1998
Endotoxin (ET)-induced liver failure is characterized by parenchymal cell apoptosis and inflammation leading to liver cell… (More)
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Highly Cited
1998
Highly Cited
1998
Caspases play a major role in the transduction of the apoptotic signal and execution of apoptosis in mammalian cells. Ectopic… (More)
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Highly Cited
1990
Highly Cited
1990
One hundred five untreated adult patients with acute lymphocytic leukemia (ALL) were entered on the vincristine, Adriamycin… (More)
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