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V(D)J recombination activating protein 2

Known as: RAG-2 protein, recombination activating gene 2 protein, RAG-2 
V(D)J recombination-activating protein 2 (527 aa, ~59 kDa) is encoded by the human RAG2 gene. This protein plays a role in the mediation of V-D-J… 
National Institutes of Health

Related topics

Related topics

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Broader (1)

DNA-Binding Proteins
Immune System ProcessesRAG2 geneRAG2 wt AlleleV(D)J Recombination

Papers overview

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2018
2018
An Allosteric Mechanism for Epigenetic Activation of the V(D)J Recombinase
V(D)J recombination, the process by which antigen receptor genes are assembled from discrete DNA segments during lymphoid… 
2016
2016
Phylogeography of Diptychus maculatus (Cyprinidae) endemic to the northern margin of the QTP and Tien Shan region
Phylogeography and historical demography of the cyprinid fish Diptychus maculatus (subfamily Schizothoracinae) are evaluated… 
2015
2015
TTTACCAAAA CCCCCTCACA CTCACCTATA TTCCTCTCTC AATCTACTTT CAATCATAAA CATTATTTTC ATTTTTCTTA CTCAAATCTC TATCTTATCT TTTACTTATC 1849 1850 TCAATTAACT CCTCTTCTCA TTTATTCTTA ACTATAACTA TTCTAATCTC TCTTTTTTAA…
The vast repertoire of immunoglobulins and T cell receptors is generated, in part, by V(D)J recombination, a series of genomic… 
Review
2006
Review
2006
[Molecular mechanisms of IgE synthesis].
B細胞の分化と機能発現 B前駆細胞は骨髄の多能性造血幹細胞に由来する. また,分化の初期段階で構成的に発現される recombination-activating gene(RAG)-1 と RAG-2 の 産物は,B細胞受容体(BCR… 
2005
2005
Dispensable sequence motifs in the RAGI and RAG-2 genes for plasmid V ( D ) J recombination ( recombination activating genes / cysteine-rich motifs / topoisomerase homology )
As a probe ofwhetherRAG-I andRAG-2 gene products activate other genes or form part of the recombinase itself, certain mutants of… 
2003
2003
The Half-Life o f R A G-1 Prote in in Precursor B Cells Is Increased in the A b s e n c e o f R A G-2 Express ion By
T he variable domains of both Ig and T C R molecules are encoded by multiple gennline V, D, and J gene segments that are… 
2002
2002
Anti-4-1 BB Monoclonal Antibody Enhances Rejection of Large Tumor Burden by Promoting Survival but not Clonal Expansion of Tumor-specific CD 8 T Cells 1
Anti-4-1BB monoclonal antibody (mAb) has been shown to induce antitumor immunity by a CD4/CD8-dependent mechanism, but its direct… 
1995
1995
Regulation studies of the human recombination activating genes, RAG-1 and RAG-2
Regdation Studies of the Human Recombination Activating Genes (RAG-1 and RAG-2) D e p z of Master of Science, 1995. Laurent Karl… 
1992
1992
Transcription of germ line V alpha segments correlates with ongoing T-cell receptor alpha-chain rearrangement
M14T is a virally transformed immature T-cell line which continues to rearrange its T-cell antigen receptor (TCR) alpha-chain… 
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