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V(D)J recombination activating protein 2

Known as: RAG-2 protein, recombination activating gene 2 protein, RAG-2 
V(D)J recombination-activating protein 2 (527 aa, ~59 kDa) is encoded by the human RAG2 gene. This protein plays a role in the mediation of V-D-J… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Regulated expression of the recombinase RAG-1 and RAG-2 proteins is necessary for generating the vast repertoire of antigen… Expand
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Highly Cited
2001
Highly Cited
2001
Mice containing livers repopulated with human hepatocytes would provide excellent in vivo models for studies on human liver… Expand
Highly Cited
1996
Highly Cited
1996
Patients with human severe combined immunodeficiency (SCID) can be divided into those with B lymphocytes (B+ SCID) and those… Expand
Highly Cited
1994
Highly Cited
1994
Detection of differentially regulated genes has been severely hampered by technical limitations. In an effort to overcome these… Expand
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Highly Cited
1994
Highly Cited
1994
To study the role of B-cell antigen CD40 in immune responses, mouse embryonic stem (ES) cells in which both copies of the gene… Expand
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Highly Cited
1993
Highly Cited
1993
Antigen receptor genes are assembled by site-specific DNA rearrangement. The recombination activator genes RAG-1 and RAG-2 are… Expand
Highly Cited
1993
Highly Cited
1993
We describe a system to evaluate the function of lymphocyte-specific and generally expressed genes in the differentiation and/or… Expand
Highly Cited
1992
Highly Cited
1992
We have generated mice that carry a germline mutation in which a large portion of the RAG-2 coding region is deleted. Homozygous… Expand
Highly Cited
1991
Highly Cited
1991
The recombination activating genes, RAG-1 and RAG-2, are likely to encode components of the V(D)J site-specific recombination… Expand
Highly Cited
1990
Highly Cited
1990
The vast repertoire of immunoglobulins and T cell receptors is generated, in part, by V(D)J recombination, a series of genomic… Expand