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Uroporphyrinogens

Known as: Uroporphyrinogen, Uroporphyrinogens [Chemical/Ingredient] 
Porphyrinogens which are intermediates in heme biosynthesis. They have four acetic acid and four propionic acid side chains attached to the pyrrole… 
National Institutes of Health

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17 relations

Narrower (4)

19-bromo-1-hydroxymethylbilaneN(D)-methyl-1-formylbilaneUroporphyrinogen IIIhydroxymethylbilane
In BloodProcess of secretionUroporphyrinogen III synthase:CCnc:Pt:Bld:QnUroporphyrinogen III synthase:CCnc:Pt:Plas:Qn

Papers overview

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2011
2011
The first branching point in porphyrin biosynthesis: A systematic docking, molecular dynamics and quantum mechanical/molecular mechanical study of substrate binding and mechanism of uroporphyrinogen…
In humans, uroporphyrinogen decarboxylase is intimately involved in the synthesis of heme, where the decarboxylation of the… 
2003
2003
PORPHYRIN BIOSYNTHESIS IN ERYTHROCYTES
The porphyrinogens are colorless, reduced porphyrins containing 6 extra atoms of hydrogen. They have been reported to occur in… 
1991
1991
Action of uroporphyrinogen decarboxylase on uroporphyrinogen-III: a reassessment of the clockwise decarboxylation hypothesis.
2. Malthus, R., Clark, D. G., Watts, C. & Sneyd, J. G. T. (1980) Biochem. J. 188, 99-106 3. Lederer, B., Van Hoof, F., Van den… 
1986
1986
Stimulatory effects of androgens on normal children's bone marrow in culture: effects on BFU-E, CFU-E, and uroporphyrinogen I synthase activity.
We studied the effect of natural and synthetic androgens on children's erythropoietic precursor cells in culture. Cultures of… 
1984
1984
Modified uroporphyrinogen decarboxylase activity in a yeast mutant which mimics porphyria cutanea tarda.
The isolation of a new mutant Sm1 strain of yeast, Saccharomyces cerevisiae, is described: this strain was partially defective in… 
1984
1984
Isolation and identification of a cDNA clone coding for rat uroporphyrinogen decarboxylase.
We have cloned and identified a DNA sequence complementary to the mRNA of uroporphyrinogen decarboxylase ( UroDCase ) from rat… 
1981
1981
Effect of chronologic age on induction of cystathionine synthase, uroporphyrinogen I synthase, and glucose-6-phosphate dehydrogenase activities in lymphocytes.
The activities of cystathionine synthase [L-serine hydro-lyase (adding homocysteine), EC 4.2.1.22], uroporphyrinogen I synthase… 
1981
1981
The diagnosis of acute intermittent porphyria. Usefulness and limitations of the erythrocyte uroporphyrinogen I synthase assay.
In acute intermittent porphyria (AIP) the inherited metabolic defect residues in a partial enzyme deficiency at the… 
1979
1979
Uroporphyrinogen I synthase induction in normal human bone marrow cultures: an early and quantitative response of erythroid differentiation.
Uroporphyrinogen I (URO) synthase [porphobilinogen ammonia-lyase (polymerizing), EC 4.3.1.8] activity increased when cultures of… 
Highly Cited
1978
Highly Cited
1978
Inhibition of dimethyl sulfoxide-stimulated Friend cell erythrodifferentiation by hydrocortisone and other steroids.
Erythrodifferentiation and hemoglobin synthesis in dimethyl sulfoxide-stimulated Friend erythroleukemia cells were inhibited by…