Uranostaphyloschisis

Gene trap mutagenesis is a powerful tool to create loss-of-function mutations in mice and other model organisms. Modifications of… Expand

Pierre Robin sequence (PRS) is an association of clinical features consisting of mandibular hypoplasia, cleft secondary palate… Expand

Nonsyndromic cleft lip and palate (CLP) is among the most common human birth defects. Transmission patterns suggest that the… Expand

Previous work suggested that cleft lip with or without cleft palate (CL/P) is genetically distinct from isolated cleft secondary… Expand

Campomelic dysplasia (CD), a semilethal human skeletal malformation syndrome with XY sex reversal, is caused by heterozygous… Expand

MSX2 is a homeodomain transcription factor that has been implicated in craniofacial morphogenesis on the basis of its expression… Expand