Ubiquinone Biosynthesis Pathway

Known as: Ubiquinone and other terpenoid-quinone biosynthesis, Ubiquinone and menaquinone biosynthesis, Ubiquinone Biosynthesis 
The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme. [GOC:mah]
National Institutes of Health

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5 relations
FNTA protein, humanFNTA wt AlleleNAD(P)H dehydrogenase (quinone) 1, humanNQO1 wt Allele
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Papers overview

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Highly Cited
2007
Highly Cited
2007
Nutrition-induced ketosis alters metabolic and signaling gene networks in liver of periparturient dairy cows.
Dairy cows are highly susceptible after parturition to developing liver lipidosis and ketosis, which are costly diseases to… (More)
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2004
2004
Crystal structure of a dodecameric FMN-dependent UbiX-like decarboxylase (Pad1) from Escherichia coli O157: H7.
The crystal structure of the flavoprotein Pad1 from Escherichia coli O157:H7 complexed with the cofactor FMN has been determined… (More)
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2000
2000
Identification of Escherichia coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis.
It was recently discovered that the aarF gene in Providencia stuartii is required for coenzyme Q (CoQ) biosynthesis. Here we… (More)
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2000
2000
Isolation and functional expression of human COQ3, a gene encoding a methyltransferase required for ubiquinone biosynthesis.
The COQ3 gene in Saccharomyces cerevisiae encodes an O-methyltransferase required for two steps in the biosynthetic pathway of… (More)
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2000
2000
Influence of peroxisome proliferator-activated receptor alpha on ubiquinone biosynthesis.
The control of ubiquinone biosynthesis by peroxisome proliferators was investigated using peroxisome proliferator activated… (More)
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Review
2000
Review
2000
Ubiquinone. Biosynthesis of quinone ring and its isoprenoid side chain. Intracellular localization.
Ubiquinone, known as coenzyme Q, was shown to be the part of the metabolic pathways by Crane et al. in 1957. Its function as a… (More)
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Highly Cited
1999
Highly Cited
1999
Expression of prokaryotic 1-deoxy-D-xylulose-5-phosphatases in Escherichia coli increases carotenoid and ubiquinone biosynthesis.
Isopentenyl diphosphate (IPP) acts as the common, five-carbon building block in the biosynthesis of all isoprenoids. The first… (More)
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1997
1997
Characterization of the COQ5 gene from Saccharomyces cerevisiae. Evidence for a C-methyltransferase in ubiquinone biosynthesis.
Ubiquinone (coenzyme Q or Q) is a lipophilic metabolite that functions in the electron transport chain in the plasma membrane of… (More)
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Highly Cited
1996
Highly Cited
1996
The COQ7 gene encodes a protein in saccharomyces cerevisiae necessary for ubiquinone biosynthesis.
Ubiquinone (coenzyme Q) is a lipid that transports electrons in the respiratory chains of both prokaryotes and eukaryotes… (More)
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1996
1996
Complementation of coq3 mutant yeast by mitochondrial targeting of the Escherichia coli UbiG polypeptide: evidence that UbiG catalyzes both O-methylation steps in ubiquinone biosynthesis.
Ubiquinone functions in the mitochondrial electron transport chain. Recent evidence suggests that the reduced form of ubiquinone… (More)
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