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UVRAG protein, human

Known as: Beclin 1 Binding Protein, DHTX protein, human, p63 
UV radiation resistance-associated gene protein (699 aa, ~78 kDa) is encoded by the human UVRAG gene. This protein is involved in both DNA repair and… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
TGFbeta ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors… Expand
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Highly Cited
2006
Highly Cited
2006
We demonstrate that deltaNp63alpha is an essential survival factor in head and neck squamous cell carcinoma (HNSCC) through its… Expand
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Highly Cited
2006
Highly Cited
2006
p63 is critical for epithelial development yet little is known about the transcriptional programmes it regulates. By… Expand
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Highly Cited
2004
Highly Cited
2004
Individuals with Li-Fraumeni syndrome carry inherited mutations in the p53 tumor suppressor gene and are predisposed to tumor… Expand
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Review
2004
Review
2004
The tumor suppressor p53 is critically important in the cellular damage response and is the founding member of a family of… Expand
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Highly Cited
2002
Highly Cited
2002
The tumour-suppressor gene p53 is frequently mutated in human cancers and is important in the cellular response to DNA damage… Expand
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Review
2002
Review
2002
The discoveries of the p53 homologs, p63 and p73, have both fueled new insights and exposed enigmas in our understanding of the… Expand
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Highly Cited
2001
Highly Cited
2001
ABSTRACT The p53 protein is related by sequence homology and function to the products of two other genes, p63 and p73, that each… Expand
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Review
2000
Review
2000
The p53 gene is the most frequently mutated gene in human cancer. The identification of two homologues, p63 and p73, revealed… Expand
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Review
2000
Review
2000
Inactivation of the tumour suppressor p53 is the most common defect in cancer cells. The discovery of its two close relatives… Expand
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