FAQ

USP2 gene

Known as: UBIQUITIN-SPECIFIC PROTEASE, 41-KD, ubiquitin specific peptidase 2, UBP41 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2018
02420022018

Papers overview

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2016
2016
Ubiquitin-specific protease 2 decreases p53-dependent apoptosis in cutaneous T-cell lymphoma
Treatment of advanced cutaneous T-cell lymphomas (CTCL) is challenging because they are resistant to conventional chemotherapy… (More)
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2015
2015
USP2 promotes cell migration and invasion in triple negative breast cancer cell lines
Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer that is often associated with a poor prognosis… (More)
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2015
2015
Peroxisomal Import Reduces the Proapoptotic Activity of Deubiquitinating Enzyme USP2
The human deubiquitinating enzyme ubiquitin-specific protease 2 (USP2) regulates multiple cellular pathways, including cell… (More)
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2014
2014
USP2 regulates the intracellular localization of PER1 and circadian gene expression.
Endogenous 24-h rhythms in physiology are driven by a network of circadian clocks located in most tissues. The molecular clock… (More)
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2014
2014
Identifying USPs regulating immune signals in Drosophila: USP2 deubiquitinates Imd and promotes its degradation by interacting with the proteasome
Rapid activation of innate immune defences upon microbial infection depends on the evolutionary conserved NF-κB dependent signals… (More)
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2014
2014
Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α2δ-1-induced downregulation of Cav1.2 channels
Availability of voltage-gated calcium channels (Cav) at the plasma membrane is paramount to maintaining the calcium homeostasis… (More)
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2012
2012
Regulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2
Endogenous 24-hour rhythms are generated by circadian clocks located in most tissues. The molecular clock mechanism is based on… (More)
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2012
2012
Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels.
BACKGROUND KCNQ1 (Kv7.1), together with its KCNE β subunits, plays a pivotal role both in the repolarization of cardiac tissue… (More)
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2012
2012
Transient kinetic analysis of USP2-catalyzed deubiquitination reveals a conformational rearrangement in the K48-linked diubiquitin substrate.
Deubiquitination has emerged as an essential regulatory mechanism of a number of cellular processes. An in-depth understanding of… (More)
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2002
2002
Parathyroid hormone (hPTH 1-38) stimulates the expression of UBP41, an ubiquitin-specific protease, in bone.
Parathyroid hormone (PTH) stimulates bone formation in both animals and humans, and the expression of a number of genes has been… (More)
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