URB 754

URB-754 (6-methyl-2-[(4-methylphenyl)amino]-1-benzoxazin-4-one) was identified as a new type of designer drug in illegal products… (More)

BACKGROUND AND PURPOSE Two compounds, URB602 and URB754, have been reported in the literature to be selective inhibitors of… (More)

BACKGROUND AND PURPOSE Cerebrovascular smooth muscle cells express the CB1 cannabinoid receptor and CB1 agonists produce… (More)

The compound URB754 was recently identified as a potent inhibitor of the endocannabinoid-deactivating enzyme monoacylglycerol… (More)

Previous studies indicate that in brain tissue the endocannabinoid 2-AG is inactivated by monoglyceride lipase (MGL)-catalyzed… (More)

Our paper identified 6-methyl-2-p-tolylaminobenzo[d]oxazin-4-one (URB754; Specs) as a monoacylglycerol lipase (MGL) inhibitor… (More)