URB 754

URB-754 (6-methyl-2-[(4-methylphenyl)amino]-1-benzoxazin-4-one) was identified as a new type of designer drug in illegal products… Expand

Sleep may promote the transfer of memories from hippocampus to cortex. New work shows that experiences are replayed during sleep… Expand

BACKGROUND AND PURPOSE Two compounds, URB602 and URB754, have been reported in the literature to be selective inhibitors of… Expand

BACKGROUND AND PURPOSE Cerebrovascular smooth muscle cells express the CB1 cannabinoid receptor and CB1 agonists produce… Expand

The compound URB754 was recently identified as a potent inhibitor of the endocannabinoid-deactivating enzyme monoacylglycerol… Expand

Our knowledge of the function of the cannabinoid system in the body has been aided by the availability of pharmacological agents… Expand

Previous studies indicate that in brain tissue the endocannabinoid 2-AG is inactivated by monoglyceride lipase (MGL)-catalyzed… Expand