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UPF1 gene

Known as: UPF1, RNA helicase and ATPase, UPF1, UP Frameshift 1 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2.
Highly Cited
2010
Highly Cited
2010
Upf1 ATPase-Dependent mRNP Disassembly Is Required for Completion of Nonsense- Mediated mRNA Decay
Highly Cited
2009
Highly Cited
2009
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay.
Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism that detects and degrades mRNAs containing premature translation… 
Highly Cited
2006
Highly Cited
2006
Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay.
Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism that degrades mRNA containing premature termination codons (PTCs… 
Highly Cited
2005
Highly Cited
2005
Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping.
Highly Cited
2005
Highly Cited
2005
Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements.
Highly Cited
2004
Highly Cited
2004
Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise
Premature termination codons induce rapid transcript degradation in eukaryotic cells through nonsense-mediated mRNA decay (NMD… 
Highly Cited
2004
Highly Cited
2004
The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells.
Highly Cited
2001
Highly Cited
2001
SDE3 encodes an RNA helicase required for post‐transcriptional gene silencing in Arabidopsis
Post‐transcriptional gene silencing (PTGS) provides protection in plants against virus infection and can suppress expression of… 
Highly Cited
2000
Highly Cited
2000
Human Upf Proteins Target an mRNA for Nonsense-Mediated Decay When Bound Downstream of a Termination Codon
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