UPF1 gene

Known as: UPF1, RNA helicase and ATPase, UPF1, UP Frameshift 1 
 
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism that detects and degrades mRNAs containing premature termination… (More)
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Highly Cited
2011
Highly Cited
2011
Upf1 is a crucial factor in nonsense-mediated mRNA decay, the eukaryotic surveillance pathway that degrades mRNAs containing… (More)
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Highly Cited
2010
Highly Cited
2010
The selective degradation of mRNAs by the nonsense-mediated decay pathway is a quality control process with important… (More)
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Highly Cited
2010
Highly Cited
2010
Cellular mRNAs exist in messenger ribonucleoprotein (mRNP) complexes, which undergo transitions during the lifetime of the mRNAs… (More)
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Highly Cited
2006
Highly Cited
2006
The eukaryotic nonsense-mediated mRNA decay (NMD) pathway degrades mRNAs carrying premature stop codons (PTC). In humans, NMD… (More)
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Highly Cited
2005
Highly Cited
2005
Eukaryotic cells coordinately regulate histone and DNA synthesis. In mammalian cells, most of the regulation of histone synthesis… (More)
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Highly Cited
2005
Highly Cited
2005
In mammalian cells, nonsense-mediated messenger RNA decay (NMD) targets newly synthesized nonsense-containing mRNA bound by the… (More)
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Highly Cited
2004
Highly Cited
2004
Premature termination codons induce rapid transcript degradation in eukaryotic cells through nonsense-mediated mRNA decay (NMD… (More)
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Highly Cited
2000
Highly Cited
2000
The Upf1 protein in yeast has been implicated in the modulation of efficient translation termination as well as in the… (More)
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Highly Cited
1998
Highly Cited
1998
All eukaryotic cells analyzed have developed mechanisms to eliminate the production of mRNAs that prematurely terminate… (More)
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