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UPF1 gene

Known as: UPF1, RNA helicase and ATPase, UPF1, UP Frameshift 1 
 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Upf1 is a crucial factor in nonsense-mediated mRNA decay, the eukaryotic surveillance pathway that degrades mRNAs containing… Expand
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Highly Cited
2010
Highly Cited
2010
Cellular mRNAs exist in messenger ribonucleoprotein (mRNP) complexes, which undergo transitions during the lifetime of the mRNAs… Expand
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Highly Cited
2008
Highly Cited
2008
The nonsense-mediated decay (NMD) pathway subjects mRNAs with premature termination codons (PTCs) to rapid decay. The conserved… Expand
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Highly Cited
2006
Highly Cited
2006
Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism that degrades mRNA containing premature termination codons (PTCs… Expand
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Highly Cited
2006
Highly Cited
2006
The eukaryotic nonsense-mediated mRNA decay (NMD) pathway degrades mRNAs carrying premature stop codons (PTC). In humans, NMD… Expand
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Highly Cited
2005
Highly Cited
2005
Decapping is a key step in mRNA turnover. However, the composition and regulation of the human decapping complex is poorly… Expand
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Highly Cited
2004
Highly Cited
2004
Premature termination codons induce rapid transcript degradation in eukaryotic cells through nonsense-mediated mRNA decay (NMD… Expand
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Highly Cited
2004
Highly Cited
2004
Members of the PI 3-kinase-related kinase (PIKK) family function in mitogenic and stress-induced signaling pathways in eukaryotic… Expand
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Highly Cited
2001
Highly Cited
2001
Post‐transcriptional gene silencing (PTGS) provides protection in plants against virus infection and can suppress expression of… Expand
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Highly Cited
2000
Highly Cited
2000
Nonsense-mediated decay (NMD) rids eukaryotic cells of aberrant mRNAs containing premature termination codons. These are… Expand
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