ULK1 protein, human

Known as: ATG1 Autophagy Related 1 Homolog, hATG1, unc-51-like kinase 1 (C. elegans) protein, human 
Serine/threonine-protein kinase ULK1 (1050 aa, ~113 kDa) is encoded by the human ULK1 gene. This protein is involved in protein phosphorylation that… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2017
0519982017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Activation of the stimulator of interferon genes (STING) pathway by microbial or self-DNA, as well as cyclic dinucleotides (CDNs… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Autophagy is a process by which components of the cell are degraded to maintain essential activity and viability in response to… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Adenosine monophosphate-activated protein kinase (AMPK) is a conserved sensor of intracellular energy activated in response to… (More)
  • figure 1
  • figure 2
  • figure 4
Is this relevant?
2011
2011
ULK1 (Unc51-like kinase, hATG1) is a Ser/Thr kinase that plays a key role in inducing autophagy in response to starvation. ULK1… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
In yeast, activation of ATG1/ATG13 kinase complex initiates autophagy. This mechanism of autophagy initiation is conserved, as… (More)
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Beta cell loss contributes to type 2 diabetes, with increased apoptosis representing an underlying mechanism. Autophagy, i.e. the… (More)
  • figure 1
  • figure 3
  • figure 2
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Following cessation of growth, yeast cells remain viable in a nondividing state for a period of time known as the chronological… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
BACKGROUND To survive starvation and other forms of stress, eukaryotic cells undergo a lysosomal process of cytoplasmic… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Eukaryotic cells have evolved strategies to respond to stress conditions. For example, autophagy in yeast is primarily a response… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Autophagy is a process in which cytosol and organelles are sequestered within double-membrane vesicles that deliver the contents… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?