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UHRF1 wt Allele
Known as:
hUHRF1
, hNP95
, huNp95
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Human UHRF1 wild-type allele is located in the vicinity of 19p13.3 and is approximately 59 kb in length. This allele, which encodes E3 ubiquitin…
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National Institutes of Health
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Related topics
Related topics
7 relations
19p13.3
DNA Methylation Regulation
Transcriptional Activation
Ubiquitinated Protein Degradation
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Crystal structure of PHD domain of UHRF1 and insights into recognition of unmodified histone H3 arginine residue 2
Lulu Hu
,
Ze Li
,
Ping Wang
,
Yan Lin
,
Yanhui Xu
Cell Research
2011
Corpus ID: 2433080
Crystal structure of PHD domain of UHRF1 and insights into recognition of unmodified histone H3 arginine residue 2
Highly Cited
2011
Highly Cited
2011
Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger
Chengkun Wang
,
Jie Shen
,
+8 authors
C. Cao
Cell Research
2011
Corpus ID: 2602694
Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger
Highly Cited
2009
Highly Cited
2009
The multi-domain protein Np95 connects DNA methylation and histone modification
Andrea Rottach
,
Carina Frauer
,
G. Pichler
,
I. M. Bonapace
,
Fabio Spada
,
H. Leonhardt
Nucleic Acids Research
2009
Corpus ID: 10819187
DNA methylation and histone modifications play a central role in the epigenetic regulation of gene expression and cell…
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Highly Cited
2007
Highly Cited
2007
UHRF1 Plays a Role in Maintaining DNA Methylation in Mammalian Cells
M. Bostick
,
Jong Kyong Kim
,
P. Estève
,
Amander T. Clark
,
S. Pradhan
,
S. Jacobsen
Science
2007
Corpus ID: 46033335
Epigenetic inheritance in mammals relies in part on robust propagation of DNA methylation patterns throughout development. We…
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Highly Cited
2007
Highly Cited
2007
ICBP90, a Novel Methyl K9 H3 Binding Protein Linking Protein Ubiquitination with Heterochromatin Formation
P. Karagianni
,
L. Amazit
,
J. Qin
,
J. Wong
Molecular and Cellular Biology
2007
Corpus ID: 21809085
ABSTRACT Methylation of histone H3 on lysine 9 is critical for diverse biological processes including transcriptional repression…
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Highly Cited
2004
Highly Cited
2004
ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain
M. Unoki
,
Toshihiko Nishidate
,
Yusuke Nakamura
Oncogene
2004
Corpus ID: 21948278
ICBP90, inverted CCAAT box-binding protein of 90 kDa, has been reported as a regulator of topoisomerase IIα expression. We…
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Highly Cited
2003
Highly Cited
2003
ICBP90 belongs to a new family of proteins with an expression that is deregulated in cancer cells
M. Mousli
,
R. Hopfner
,
+5 authors
C. Bronner
British Journal of Cancer
2003
Corpus ID: 2931668
ICBP90 (Inverted CCAAT box Binding Protein of 90 kDa) is a recently identified nuclear protein that binds to one of the inverted…
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Highly Cited
2002
Highly Cited
2002
Targeted Disruption of Np95 Gene Renders Murine Embryonic Stem Cells Hypersensitive to DNA Damaging Agents and DNA Replication Blocks*
M. Muto
,
Y. Kanari
,
+4 authors
K. Tatsumi
Journal of Biological Chemistry
2002
Corpus ID: 44936843
NP95, which contains a ubiquitin-like domain, a cyclin A/E-Cdk2 phosphorylation site, a retinoblastoma (Rb) binding motif, and a…
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Highly Cited
2002
Highly Cited
2002
Np95 is regulated by E1A during mitotic reactivation of terminally differentiated cells and is essential for S phase entry
I. M. Bonapace
,
L. Latella
,
+5 authors
P. P. Di Fiore
Journal of Cell Biology
2002
Corpus ID: 15337625
Terminal differentiation exerts a remarkably tight control on cell proliferation. However, the oncogenic products of DNA tumor…
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Highly Cited
2000
Highly Cited
2000
ICBP90, a novel human CCAAT binding protein, involved in the regulation of topoisomerase IIalpha expression.
R. Hopfner
,
M. Mousli
,
+6 authors
Christian Bronner
Cancer Research
2000
Corpus ID: 42846426
The one-hybrid system with an inverted CCAAT box as the DNA target sequence was used to identify proteins acting on key DNA…
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