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UGT2B17 gene

Known as: UGT2B17, UDP Glucuronosyltransferase 2 Family, Polypeptide B17 Gene, URIDINE DIPHOSPHATE GLYCOSYLTRANSFERASE 2 FAMILY, MEMBER B17 
This gene plays a role in detoxification of steroids and xenobiotics.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
AIM Among the genes of drug-metabolizing enzymes, CYP2D6 is notoriously difficult to characterize owing to the complexity of gene… Expand
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Highly Cited
2008
Highly Cited
2008
Osteoporosis, a highly heritable disease, is characterized mainly by low bone-mineral density (BMD), poor bone geometry, and/or… Expand
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Highly Cited
2008
Highly Cited
2008
Metabolism of androgens includes glucuronidation, the major pathway of steroid elimination in several steroid target tissues… Expand
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Highly Cited
2007
Highly Cited
2007
CONTEXT Previous in vitro studies have demonstrated that the UDP glucuronosyltransferase (UGT)2B15 and UGT2B17 glucuronidate… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND UDP-glucuronosyltransferase (UGT) 2B17 is a phase II metabolizing enzyme that mediates the glucuronidation of C(19… Expand
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Highly Cited
2007
Highly Cited
2007
OBJECTIVES Androgens, especially dihydrotestosterone, have been postulated to modify the risk of prostate cancer. 3-Beta… Expand
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Highly Cited
2006
Highly Cited
2006
Purpose: UDP-glucuronosyltransferases (UGT) are a family of enzymes that glucuronidate many endogenous chemicals, including… Expand
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Highly Cited
2005
Highly Cited
2005
The nicotine-derived tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), is one of the most… Expand
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Highly Cited
2004
Highly Cited
2004
Members of the human UDP-glucuronosyltransferase 2B family are located in a cluster on chromosome 4q13 and code for enzymes whose… Expand
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Highly Cited
2003
Highly Cited
2003
Minor histocompatibility antigens (minor H antigens) are targets of graft-versus-host disease and graft-versus-leukemia responses… Expand
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