UGT1A9 protein, human

Known as: lugP4, UDP-Glucuronosyltransferase 1-I, UGT-1I 
UDP-glucuronosyltransferase 1-9 (530 aa, ~60 kDa) is encoded by the human UGT1A9 gene. This protein is involved in the metabolism of phenolic… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
UDP-glucuronosyltransferases (UGTs) catalyze glucuronidation of a variety of xenobiotics and endobiotics. UGTs are divided into… (More)
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2009
2009
Mycophenolate mofetil (MMF) is an immunosuppressive drug commonly used in the context of kidney transplantation. Exposure to the… (More)
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2007
2007
We established stable HEK293 cell lines expressing double isoforms, UGT1A1 and UGT1A9, UGT1A4 and UGT1A9, or UGT1A6 and UGT1A9… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE Capecitabine and irinotecan are commonly used in the treatment of metastatic colorectal cancer (CRC). We hypothesized… (More)
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Highly Cited
2004
Highly Cited
2004
The human UDP-glucuronosyltransferase, UGT1A9, catalyses glucuronidations of various endobiotics and xenobiotics. In the present… (More)
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Highly Cited
2002
Highly Cited
2002
7-Ethyl-10-hydroxycamptothecin (SN-38) is the pharmacologically active metabolite of irinotecan, in addition to being responsible… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND AND AIMS The liver represents one of the major sites of human glucuronidation. Many therapeutic drugs are substrates… (More)
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Highly Cited
2002
Highly Cited
2002
(R,S)-Oxazepam is a 1,4-benzodiazepine anxiolytic drug that is metabolized primarily by hepatic glucuronidation. In previous… (More)
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Highly Cited
2001
Highly Cited
2001
In the current study, the identification of the rat and human UDP-glucuronosyltransferase (UGT) isoforms responsible for the… (More)
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Highly Cited
1997
Highly Cited
1997
Family 1 UDP-glucuronosyltransferases (UGTs) (UGT1A) are encoded by a locus that predicts the existence of at least nine… (More)
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