UGT1A9 gene

Known as: UGT1A9, LUGP4, HLUGP4 
This gene is involved in phenol detoxification.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
PURPOSE UGT1A1*28 is considered the main pharmacogenetic predictor of the toxicity outcome of irinotecan-treated patients. We… (More)
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2009
2009
Mycophenolate mofetil (MMF) is an immunosuppressive drug commonly used in the context of kidney transplantation. Exposure to the… (More)
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2007
2007
We established stable HEK293 cell lines expressing double isoforms, UGT1A1 and UGT1A9, UGT1A4 and UGT1A9, or UGT1A6 and UGT1A9… (More)
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2007
2007
INTRODUCTION The immunosuppressive agent mycophenolic acid (MPA) is metabolized by uridine diphosphate glucuronosyltransferase… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE To determine whether uridine diphosphate-glucuronosyltransferase 1A1, UGT1A7, and UGT1A9 polymorphisms affect the… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE Capecitabine and irinotecan are commonly used in the treatment of metastatic colorectal cancer (CRC). We hypothesized… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Mycophenolic acid (MPA), an effective immunosuppressive drug used in renal transplantation, is extensively… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVES Polymorphisms in UDP-glucuronosyltransferases (UGTs) can influence detoxifying capacities and have considerable… (More)
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Highly Cited
2004
Highly Cited
2004
The human UDP-glucuronosyltransferase, UGT1A9, catalyses glucuronidations of various endobiotics and xenobiotics. In the present… (More)
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Highly Cited
2003
Highly Cited
2003
In vitro metabolic studies revealed that along with UDP-glucuronosyltransferase (UGT) 1A1, the hepatic UGT1A9 and the… (More)
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