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UDP-glucuronosyltransferase, UGT1A8

Known as: UGT1A8 
National Institutes of Health

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Broader (1)

Glucuronosyltransferase
UGT1A8 gene

Papers overview

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2016
2016
In vitro stereoselective inhibition of ginsenosides toward UDP-glucuronosyltransferase (UGT) isoforms.
2015
2015
Regulation profile of phosphatidylcholines (PCs) and lysophosphatidylcholines (LPCs) components towards UDP-glucuronosyltransferases (UGTs) isoforms
Abstract 1. Endogenous compounds have been reported to be the regulators of UDP-glucuronosyltransferases (UGTs) isoforms. This… 
2010
2010
Effects of Andrographis paniculata and Orthosiphon stamineus Extracts on the Glucuronidation of 4-Methylumbelliferone in Human UGT Isoforms
The effects of Andrographis paniculata and Orthosiphon stamineus extracts on the in vitro glucuronidation of 4… 
2009
2009
Key Amino Acid Residues Responsible for the Differences in Substrate Specificity of Human UDP-Glucuronosyltransferase (UGT)1A9 and UGT1A8
Human UDP-glucuronosyltransferase (UGT)1A9 is one of the major isoforms in liver and extrahepatic tissues, catalyzing the… 
2009
2009
The Role of Human UDP-Glucuronyltransferases on the Formation of the Methylenedioxymethamphetamine (Ecstasy) Phase II Metabolites R- and S-3-Methoxymethamphetamine 4-O-Glucuronides
Different pharmacokinetic properties have been observed for the two enantiomers of the entactogen 3,4-methylendioxy… 
2008
2008
Glucuronidation of Monohydroxylated Warfarin Metabolites by Human Liver Microsomes and Human Recombinant UDP-Glucuronosyltransferases
Our understanding of human phase II metabolic pathways which facilitate detoxification and excretion of warfarin (Coumadin) is… 
2007
2007
Hepatocyte nuclear factor1 transcription factors are essential for the UDP-glucuronosyltransferase 1A9 promoter response to hepatocyte nuclear factor 4&agr;
In humans, UDP-glucuronosyltransferase 1A9 is known to glucuronidate numerous lipophilic substances of pharmacological and… 
2007
2007
Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms.
We characterized the in vitro glucuronidation of prunetin, a prodrug of genistein that is a highly active cancer prevention agent… 
2005
2005
ANALYSIS OF SUBSTRATE SPECIFICITIES AND TISSUE EXPRESSION OF RAT UDP-GLUCURONOSYLTRANSFERASES UGT1A7 AND UGT1A8
The UGT1 complex codes for a subfamily of homologous “1A7-like” UDP-glucuronosyltransferases (UGTs), including UGT1A7 and UGT1A8… 
2005
2005
Activity and Expression of Various Isoforms of Uridine Diphosphate Glucuronosyltransferase are Differentially Regulated During Hepatic Regeneration in Rats
PurposeGlucuronidation pathway is very important in the detoxification of endogenous and exogenous compounds. The objective of… 
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