UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity

Known as: LacCer synthase activity, UDP-galactose glucosylceramide beta-1,4-galactosyltransferase activity, lactosylceramide synthase activity 
Catalysis of the reaction: UDP-D-galactose + a glucosylceramide = a lactosylceramide + uridine-5'-diphosphate. The glucosylceramide has sphinganine… (More)
National Institutes of Health

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1994-2013
0119942013

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2014
2014
BACKGROUND Glycosphingolipids, integral components of the cell membrane, have been shown to serve as messengers, transducing… (More)
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2013
2013
Glycosphingolipids are expressed on the cell membrane and act as important factors in various events that occur across the plasma… (More)
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2010
2010
Glycosphingolipids (GSLs) are important for various biological functions in the nervous system, the immune system, embryogenesis… (More)
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2008
2008
Angiogenesis is largely driven by vascular endothelial growth factor (VEGF). However, the role of lipid second messengers such as… (More)
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2007
2007
Trichothecenes are sesquiterpenoid metabolites produced by several fungal strains that impair human and animal health. Since… (More)
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2005
2005
Recent molecular cloning studies have suggested the presence of at least two β4Gal transferase genes (β4GalT-V and β4GalT-VI… (More)
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1997
1997
Sphingolipid biosynthesis in synchronized HeLa cells was studied by pulse labeling with [14C]Ser or [14C]Gal and a simple TLC… (More)
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1994
1994
Introduction of an epoxide function at the C4 position of the glucose moiety of a truncated glucosylceramide (GlcCer) yields two… (More)
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