UDP-N-acetylmuramate-L-alanine ligase activity

Known as: UDP-N-acetylmuramate:L-alanine ligase (ADP-forming), UDP-MurNAc:L-alanine ligase activity, UDPMurNAc-L-alanine synthetase activity 
Catalysis of the reaction: L-alanine + ATP + UDP-N-acetylmuramate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanine. [EC:6.3.2.8, RHEA… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2016
01219732016

Papers overview

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2011
2011
We previously isolated a mutant hypersensitive to L-alanyl-L-alanine from a non-L-alanine-metabolizing Escherichia coli strain… (More)
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2006
2006
UDPMurNAc-L-Ala-gamma-D-Glu-X-D-Ala-DAla (X = L-Lys or m-DAP) is the cytoplasmic precursor for the lipid-linked cycle of… (More)
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2005
2005
Uptake and metabolism of L-alanine by freshly isolated trout hepatocytes has been analyzed. This amino acid is incorporated… (More)
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2004
2004
The amino acid L-alanine has been shown to exert long-term cytoprotection by as yet unidentified molecular mechanisms. Using… (More)
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2002
2002
Benzylidene rhodanines are novel inhibitors of UDP N-acetylmuramate/L-alanine ligase. They showed selective whole-cell activity… (More)
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2002
2002
Early experiments indicated that islet beta-cells substantially metabolized L-alanine but that insulin secretion was largely… (More)
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2002
2002
Early experiments indicated that islet -cells substantially metabolized L-alanine but that insulin secretion was largely… (More)
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1997
1997
Initial velocity methods were used to probe the kinetic mechanism of Escherichia coli uridine diphosphate-N-acetylmuramate:L… (More)
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1996
1996
In the peptidoglycan biosynthesis pathway in Escherichia coli, UDP-N-acetylmuramate:L-alanine ligase (MurC) catalyzes the… (More)
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1996
1996
Biosynthesis of the Escherichia coli CS31A surface antigen was subject to phase-variation control and repressed by L-alanine… (More)
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