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UDP-N-acetylmuramate-L-alanine ligase activity

Known as: UDP-N-acetylmuramate:L-alanine ligase (ADP-forming), UDP-MurNAc:L-alanine ligase activity, UDPMurNAc-L-alanine synthetase activity 
Catalysis of the reaction: L-alanine + ATP + UDP-N-acetylmuramate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanine. [EC:6.3.2.8, RHEA… 
National Institutes of Health

Papers overview

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2020
2020
Tuberculosis (TB) is a major global heath burden, with 1.6 million people succumbing to the disease every year. The search for… 
Highly Cited
2003
Highly Cited
2003
ABSTRACT Chlamydiae are unusual obligate intracellular bacteria that cause serious infections in humans. Chlamydiae contain genes… 
Highly Cited
2000
Highly Cited
2000
ABSTRACT In the peptidoglycan of Mycobacterium leprae,l-alanine of the side chain is replaced by glycine. When expressed in… 
Review
1998
Review
1998
  • P. Reynolds
  • Cellular and Molecular Life Sciences CMLS
  • 1998
  • Corpus ID: 31941276
Abstract. Resistance to glycopeptide antibiotics in enterococci results from the synthesis of peptidoglycan precursors with low… 
Highly Cited
1997
Highly Cited
1997
Using the maltose-binding protein (MBP) fusion vector pMAL-c1 from C. V. Maina et al. (1988, Gene 74, 365-373), we have… 
Highly Cited
1997
Highly Cited
1997
Initial velocity methods were used to probe the kinetic mechanism of Escherichia coli uridine diphosphate-N-acetylmuramate:L… 
1996
1996
Uridine diphosphate N-acetylmuramate:L-alanine ligase (EC 6.3.2.8, UNAM:L-Ala ligase or MurC gene product) adds the first amino… 
Highly Cited
1996
Highly Cited
1996
In the peptidoglycan biosynthesis pathway in Escherichia coli, UDP-N-acetylmuramate:L-alanine ligase (MurC) catalyzes the… 
1996
1996
The UDP-N-acetylmuramate:L-alanine ligase of Escherichia coli is responsible for the addition of the first amino acid of the… 
Highly Cited
1995
Highly Cited
1995
The UDP-N-acetylmuramate:L-alanine ligase of Escherichia coli was over-produced in strains harbouring recombinant plasmids…