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UCHL5 gene

Known as: INO80 complex subunit R, ubiquitin C-terminal hydrolase L5, UCH37 
 
National Institutes of Health

Papers overview

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2019
2019
Auranofin is a gold (I)-containing compound used for the treatment of rheumatic arthritis. Auranofin has anticancer activity in… Expand
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2018
2018
The Hedgehog (Hh) signaling pathway plays important roles in developmental processes including pattern formation and tissue… Expand
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2017
2017
Proteasome–ubiquitin receptor hRpn13/Adrm1 binds and activates deubiquitinating enzyme Uch37/UCHL5 and is targeted by bis… Expand
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2016
2016
Transforming growth factor β-1 (TGFβ-1)-induced phosphorylation of transcription factors Smad2 and Smad3 plays a crucial role in… Expand
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2015
2015
Deubiquitinase enzymes (DUBs) of the proteasomal 19S regulatory particle are emerging as important therapeutic targets in several… Expand
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Highly Cited
2014
Highly Cited
2014
Proteasome inhibitors have demonstrated that targeting protein degradation is effective therapy in multiple myeloma (MM). Here we… Expand
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2009
2009
Ubiquitin C-terminal hydrolases (UCHs) are one of five sub-families of de-ubiquitinating enzymes (DUBs) that hydrolyze the C… Expand
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Highly Cited
2008
Highly Cited
2008
We determined composition and relative roles of deubiquitylating proteins associated with the 26S proteasome in mammalian cells… Expand
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Highly Cited
2008
Highly Cited
2008
Deubiquitinating enzymes (DUBs) are proteases that can antagonize ubiquitin-mediated signaling by disassembling ubiquitin-protein… Expand
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Highly Cited
2006
Highly Cited
2006
Uch37 is one of the three principal deubiquitinating enzymes (DUBs), and the only ubiquitin carboxy-terminal hydrolase (UCH… Expand
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