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UCHL5 gene

Known as: INO80 complex subunit R, ubiquitin C-terminal hydrolase L5, UCH37 
 
National Institutes of Health

Papers overview

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2019
2019
Auranofin is a gold (I)-containing compound used for the treatment of rheumatic arthritis. Auranofin has anticancer activity in… Expand
Highly Cited
2017
Highly Cited
2017
Proteasome–ubiquitin receptor hRpn13/Adrm1 binds and activates deubiquitinating enzyme Uch37/UCHL5 and is targeted by bis… Expand
2015
2015
Deubiquitinase enzymes (DUBs) of the proteasomal 19S regulatory particle are emerging as important therapeutic targets in several… Expand
Highly Cited
2015
Highly Cited
2015
The ubiquitin–proteasome system (UPS) is increasingly recognized as a therapeutic target for the development of anticancer… Expand
Highly Cited
2014
Highly Cited
2014
Proteasome inhibitors have demonstrated that targeting protein degradation is effective therapy in multiple myeloma (MM). Here we… Expand
Highly Cited
2010
Highly Cited
2010
Rpn13 is a novel mammalian proteasomal receptor that has recently been identified as an amplification target in ovarian cancer… Expand
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Highly Cited
2008
Highly Cited
2008
We determined composition and relative roles of deubiquitylating proteins associated with the 26S proteasome in mammalian cells… Expand
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Highly Cited
2008
Highly Cited
2008
Deubiquitinating enzymes (DUBs) are proteases that can antagonize ubiquitin-mediated signaling by disassembling ubiquitin-protein… Expand
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Highly Cited
2006
Highly Cited
2006
Uch37 is one of the three principal deubiquitinating enzymes (DUBs), and the only ubiquitin carboxy-terminal hydrolase (UCH… Expand
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Highly Cited
2006
Highly Cited
2006
TGF-β (transforming growth factor-β) signals through serine/threonine kinase receptors and intracellular Smad transcription… Expand
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