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U2AF1 gene

Known as: U2 SMALL NUCLEAR RIBONUCLEOPROTEIN AUXILIARY FACTOR, 35-KD SUBUNIT, U2 small nuclear RNA auxiliary factor 1, RN 
This gene is involved in the splicing of mRNA.
National Institutes of Health

Related topics

Related topics

10 relations
Homo sapiensIntracellular TransportLigand BindingMolecular Transport

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
DLX4 hypermethylation is a prognostically adverse indicator in de novo acute myeloid leukemia
Hypermethylation of distal-less homeobox 4 (DLX4) has been increasingly identified in several cancers. Our study was aimed to… 
2015
2015
Preferential occurrence of spliceosome mutations in acute myeloid leukemia with preceding myelodysplastic syndrome and/or myelodysplasia morphology
Spliceosome mutations are associated with myelodysplasia. Here, we aimed to evaluate the frequency and clinical associations of… 
2014
2014
A New Strategy of RNA Interference That Targets Heterologous Sequences Reveals CITFA1 as an Essential Component of Class I Transcription Factor A in Trypanosoma brucei
ABSTRACT Conditional gene silencing by RNA interference in Trypanosoma brucei can be inconclusive if knockdowns are inefficient… 
2008
2008
Splicing Factor SPF30 Bridges an Interaction between the Prespliceosome Protein U2AF35 and Tri-small Nuclear Ribonucleoprotein Protein hPrp3*
Spliceosome assembly is a dynamic process involving the sequential recruitment and rearrangement of small nuclear… 
2007
2007
Nuclear protein profiling of Jurkat cells during heat stress‐induced apoptosis by 2‐DE and MS/MS
Heat stress causes severe constraints on numerous physiological functions of cells, such as the repression of splicing of mRNA… 
2005
2005
Substrate-dependent Differences in U2AF Requirement for Splicing in Adenovirus-infected Cell Extracts*
U2AF has been characterized as an essential splicing factor required for efficient recruitment of U2 small nuclear… 
2005
2005
CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing.
2003
2003
The Structure of the Zinc Finger Domain from Human Splicing Factor ZNF265 Fold*
Identification of the protein domains that are responsible for RNA recognition has lagged behind the characterization of protein… 
1999
1999
Structures, sequence characteristics, and synteny relationships of the transcription factor E4TF1, the splicing factor U2AF35 and the cystathionine beta synthetase genes from Fugu rubripes.
1996
1996
The gene for human U2 snRNP auxiliary factor small 35-kDa subunit (U2AF1) maps to the progressive myoclonus epilepsy (EPM1) critical region on chromosome 21q22.3.
We used targeted exon trapping to clone portions of genes from human chromosome 21q22.3. One trapped sequence showed complete… 
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