U2AF1 gene

Known as: U2 SMALL NUCLEAR RIBONUCLEOPROTEIN AUXILIARY FACTOR, 35-KD SUBUNIT, U2 small nuclear RNA auxiliary factor 1, RN 
This gene is involved in the splicing of mRNA.

Topic mentions per year

Topic mentions per year

1988-2018
0204019882018

Papers overview

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Highly Cited
2014
Highly Cited
2014
Calreticulin (CALR) mutations were recently described in JAK2 and MPL unmutated primary myelofibrosis (PMF) and essential… (More)
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Highly Cited
2013
Highly Cited
2013
PURPOSE Several prognostic scoring systems have been proposed for chronic myelomonocytic leukemia (CMML), a disease in which some… (More)
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Highly Cited
2012
Highly Cited
2012
Lung adenocarcinoma, the most common subtype of non-small cell lung cancer, is responsible for more than 500,000 deaths per year… (More)
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Highly Cited
2012
Highly Cited
2012
Mutations in genes of the splicing machinery have been described recently in myelodysplastic syndromes (MDS). In the present… (More)
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Highly Cited
2012
Highly Cited
2012
A cohort of MDS patients was examined for mutations affecting 4 splice genes (SF3B1, SRSF2, ZRSR2, and U2AF35) and evaluated in… (More)
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Highly Cited
2011
Highly Cited
2011
Myelodysplastic syndromes (MDS) are hematopoietic stem cell disorders that often progress to chemotherapy-resistant secondary… (More)
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Highly Cited
1999
Highly Cited
1999
In metazoans, spliceosome assembly is initiated through recognition of the 5' splice site by U1 snRNP and the polypyrimidine… (More)
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Highly Cited
1999
Highly Cited
1999
The protein Sex-lethal (SXL) controls dosage compensation in Drosophila by inhibiting the splicing and translation of male… (More)
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Highly Cited
1996
Highly Cited
1996
The splicing factor U2AF (U2 snRNP auxiliary factor) is a heterodimer with subunits of 65 and 35 kD (U2AF65 and U2AF35). U2AF65… (More)
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Highly Cited
1993
Highly Cited
1993
Specific recognition and pairing of the 5' and 3' splice sites are critical steps in pre-mRNA splicing. We report that the… (More)
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