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U 76073

Known as: U-76,073, U-76073 
 
National Institutes of Health

Papers overview

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1999
1999
SummaryCarzelesin is a cyclopropylpyrroloindole analogue which acts as a DNA-sequence-specific alkylating agent. In this phase I… Expand
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1998
1998
Abstract We investigated the pharmacokinetic behavior of carzelesin in 31 patients receiving this drug by 10-min intravenous… Expand
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1996
1996
Carzelesin (U-80244), one of the synthetic DNA minor groove binding cyclopropylpyrroloindole analogues, was selected for clinical… Expand
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1996
1996
The chemical stability of the novel anticancer agent carzelesin in aqueous buffer/acetonitrile (1:1, v/v) mixtures has been… Expand
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1994
1994
Carzelesin (U80,244, I) is a cyclopropylpyrroloindole prodrug analog. The compound exerts its cytotoxic activity after conversion… Expand
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Highly Cited
1992
Highly Cited
1992
The cyclopropylpyrroloindole analogues are DNA minor-groove binders containing a cyclopropyl group, which mediates N3-adenine… Expand
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