U 76073

Known as: U-76,073, U-76073 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

BenzofuransIndoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1999
1999
Phase I study of Carzelesin (U-80,244) given (4-weekly) by intravenous bolus schedule
SummaryCarzelesin is a cyclopropylpyrroloindole analogue which acts as a DNA-sequence-specific alkylating agent. In this phase I… (More)
  • figure 1
  • table 1
  • table 2
  • table 3
  • table 4
Is this relevant?
1998
1998
A clinical pharmacokinetics study of carzelesin given by short-term intravenous infusion in a phase I study
We investigated the pharmacokinetic behavior of carzelesin in 31 patients receiving this drug by 10-min intravenous infusion in a… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1996
1996
Phase I clinical and pharmacokinetic study of carzelesin (U-80244) given daily for five consecutive days.
Carzelesin (U-80244), one of the synthetic DNA minor groove binding cyclopropylpyrroloindole analogues, was selected for clinical… (More)
  • figure 1
  • figure 1
  • table 1
  • table 3
  • table 4
Is this relevant?
1996
1996
Systematic study on the chemical stability of the prodrug antitumor agent carzelesin (U-80,244)
The chemical stability of the novel anticancer agent carzelesin in aqueous buffer/acetonitrile (1:1, v/v) mixtures has been… (More)
Is this relevant?
1992
1992
Cytotoxicity and antitumor activity of carzelesin, a prodrug cyclopropylpyrroloindole analogue.
The cyclopropylpyrroloindole analogues are DNA minor-groove binders containing a cyclopropyl group, which mediates N3-adenine… (More)
  • figure 1
  • figure 2
  • table 2
  • table 1
  • table 3
Is this relevant?