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U 51605

Known as: U-51605 
 
National Institutes of Health

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1 relation

Broader (1)

azo analog I

Papers overview

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2013
2013
Estradiol-17&bgr; and its Cytochrome P450- and Catechol-O-Methyltransferase–Derived Metabolites Selectively Stimulate Production of Prostacyclin in Uterine Artery Endothelial Cells: Role of Estrogen…
Metabolism of estradiol-17&bgr; to 2-hydroxyestradiol, 4-hydroxyestradiol, 2-methoxyestradiol, and 4-methoxyestradiol contributes… Expand
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Highly Cited
2006
Highly Cited
2006
In SHR aorta, calcium ionophore A-23187 releases prostacyclin and thromboxane A2 as endothelium-derived contracting factors.
In mature spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY), acetylcholine and the calcium ionophore A-23187… Expand
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2005
2005
Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8.
Recombinant CYP4F8 and CYP4F12 metabolize prostaglandin H2 (PGH2) analogs by omega2- and omega3-hydroxylation and arachidonic… Expand
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Highly Cited
2000
Highly Cited
2000
Identification of CYP4F8 in Human Seminal Vesicles as a Prominent 19-Hydroxylase of Prostaglandin Endoperoxides*
A novel cytochrome P450, CYP4F8, was recently cloned from human seminal vesicles. CYP4F8 was expressed in yeast. Recombinant… Expand
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1999
1999
Inhibition of spontaneous smooth muscle contractions in rat and rabbit intestine by blockers of the thromboxane A2 pathway.
The effect of inhibitors of the thromboxane A2 pathway on spontaneous contractions of intestinal smooth muscle preparations was… Expand
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1986
1986
Prostacyclin and steroidogenesis in goat ovarian cell types in vitro.
Granulosa, theca and corpus luteum cells of the goat ovary were isolated and incubated separately for 6 hours, with or without… Expand
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1985
1985
Absence of prostacyclin involvement in angiotensin-induced aldosterone secretion in rat adrenal cells.
The role of prostaglandins (PGs) in aldosterone secretion was studied in isolated rat adrenal glomerulosa cells. [14C]Arachidonic… Expand
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Highly Cited
1982
Highly Cited
1982
Synergistic activation by collagen and 15-hydroxy-9 alpha,11 alpha-peroxidoprosta-5,13-dienoic acid (PGH2) of phosphatidylinositol metabolism and arachidonic acid release in human platelets.
Collagen stimulates the activation of phosphatidylinositol (PI)-specific phospholipase C (EC 3.1.4.10) in human platelets, as… Expand
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1981
1981
Modification of human platelet response to sodium arachidonate by membrane modulation.
Previous studies have shown that the majority of mongrel dogs have platelets that do not aggregate when stirred with sodium… Expand
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1977
1977
Thromboxane synthetase inhibitors as pharmacological tools: differential biochemical and biological effects on platelet suspensions.
The comparative effects of three so called "thromboxane-synthetase-inhibitors" (imidazole, N-0164, and U-51605) on arachidonate… Expand
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