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Tyrosine-tRNA Ligase
Known as:
Tyrosine-tRNA Ligase [Chemical/Ingredient]
, Tyr tRNA Ligase
, Tyrosine tRNA Ligase
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Tyrosine-tRNA ligase, cytoplasmic (528 aa, ~59 kDa) is encoded by the human YARS gene. This protein is involved in the attachment of tyrosine to its…
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National Institutes of Health
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Related topics
Related topics
16 relations
Apoptosis
Cytoplasm
Enzyme Gene
Genetic Translation Process
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Theoretical and experimental biology in one —
Sheng-Xiang Lin
,
J. Lapointe
2013
Corpus ID: 11998545
It has been a dream that theoretical biology can be extensively applied in experimental biology to accelerate the understanding…
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2000
2000
SB-219383, a novel tyrosyl tRNA synthetase inhibitor from a Micromonospora sp. II. Structure determination.
C. S. Houge-Frydrych
,
S. Readshaw
,
David Bell
Journal of antibiotics (Tokyo. )
2000
Corpus ID: 31310677
A novel tyrosyl tRNA synthetase inhibitor, SB-219383, has been isolated from a Micromonospora sp. The structure of SB-219383 has…
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1993
1993
Mutational and kinetic analysis of a mobile loop in tyrosyl-tRNA synthetase.
E. A. First
,
A. Fersht
Biochemistry
1993
Corpus ID: 33723619
The role of a mobile loop in tyrosyl-tRNA synthetase has been investigated by mutating each amino acid in the loop and…
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Highly Cited
1986
Highly Cited
1986
Natural variation of tyrosyl-tRNA synthetase and comparison with engineered mutants.
M. Jones
,
D. M. Lowe
,
T. Borgford
,
A. Fersht
Biochemistry
1986
Corpus ID: 33651953
We report the cloning and sequence analysis of the gene for the tyrosyl-tRNA synthetase from Bacillus caldotenax and properties…
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1986
1986
Internal thermodynamics of position 51 mutants and natural variants of tyrosyl-tRNA synthetase.
C. Ho
,
A. Fersht
Biochemistry
1986
Corpus ID: 24361944
Natural variation and evolution impose structural changes on an enzyme that can affect the energetics of catalysis. The energy…
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1985
1985
Fine structure-activity analysis of mutations at position 51 of tyrosyl-tRNA synthetase.
A. Fersht
,
A. Wilkinson
,
P. Carter
,
G. Winter
Biochemistry
1985
Corpus ID: 37817622
Residue Thr-51 at the active site of tyrosyl-tRNA synthetase (Bacillus stearothermophilus) has been replaced with all the smaller…
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1985
1985
Reversible dissociation of dimeric tyrosyl-tRNA synthetase by mutagenesis at the subunit interface.
D. H. Jones
,
A. J. McMillan
,
A. Fersht
,
G. Winter
Biochemistry
1985
Corpus ID: 41576982
Dimeric tyrosyl-tRNA synthetase from Bacillus stearothermophilus exhibits half-of-the-sites reactivity and negative cooperativity…
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1982
1982
Cloning and amplified expression of the tyrosyl-tRNA synthetase genes of Bacillus stearothermophilus and Escherichia coli.
D. Barker
European Journal of Biochemistry
1982
Corpus ID: 27884594
Two fragments of DNA which carry the genes coding for the tyrosyl-tRNA synthetases of Escherichia coli and Bacillus…
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1974
1974
Peptide mapping of aminoacyl-tRNA synthetases: evidence for internal sequence homology in Escherichia coli leucyl-tRNA synthetase.
R. M. Waterson
,
W. Konigsberg
Proceedings of the National Academy of Sciences…
1974
Corpus ID: 5224604
Most aminoacyl-tRNA synthetases contain polypeptide chains of about either 50,000 or 100,000 daltons. Peptide mapping of tryptic…
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1971
1971
Primary sequence of tRNA-Val-1 from Escherichia coli B. II. Isolation of large fragments by limited digestion with RNases, and overlapping of fragments to reduce the total primary sequence.
F. Kimura
,
F. Harada
,
S. Nishimura
Biochemistry
1971
Corpus ID: 33697043
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