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Tyrosinase, human

Known as: TYR, Monophenol Monooxygenase, EC 1.14.18.1 
Tyrosinase (529 aa, ~60 kDa) is encoded by the human TYR gene. This protein is involved in pigment biosynthesis, eye development and the metabolism… 
National Institutes of Health

Related topics

Related topics

12 relations
Catechol OxidaseEnzyme GeneMelanogenesisMelanogenesis Pathway

Broader (1)

MONOPHENOL MONOOXYGENASE

Papers overview

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Highly Cited
2004
Highly Cited
2004
Phenoloxidase activity in Apis mellifera honey bee pupae, and ecdysteroid-dependent expression of the prophenoloxidase mRNA.
Highly Cited
1995
Highly Cited
1995
Nucleotide sequence of the cDNA encoding the proenzyme of phenol oxidase A1 of Drosophila melanogaster.
Clones encoding pro-phenol oxidase [pro-PO; zymogen of phenol oxidase (monophenol, L-dopa:oxygen oxidoreductase, EC 1.14.18.1… 
1994
1994
Molecular basis of dark-eyed albinism in the mouse.
Dark-eyed albino (C44H) is a recessive allele at the mouse albino (c) locus, which encodes tyrosinase (monophenol,L-dopa:oxygen… 
Highly Cited
1991
Highly Cited
1991
The mouse tyrosinase promoter is sufficient for expression in melanocytes and in the pigmented epithelium of the retina.
The mouse c locus encodes tyrosinase (monophenol monooxygenase; monophenol, L-dopa:oxygen oxidoreductase, EC 1.14.18.1), the key… 
Highly Cited
1988
Highly Cited
1988
Tyrosinases of murine melanocytes with mutations at the albino locus.
Tyrosinase (monophenol monooxygenase; monophenol, L-dopa:oxygen oxidoreductase, EC 1.14.18.1) is a key enzyme in the synthesis of… 
Highly Cited
1988
Highly Cited
1988
Human tyrosinase gene, mapped to chromosome 11 (q14----q21), defines second region of homology with mouse chromosome 7.
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