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Type II site-specific deoxyribonuclease

Known as: type II site specific deoxyribonuclease, Type II Site-Specific Deoxyribonucleases, DNase, Site Specific, Type II 
Enzyme systems containing a single subunit and requiring only magnesium for endonucleolytic activity. The corresponding modification methylases are… 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
DNase II digests DNA in endolysosomes. In the absence of DNase II, undigested DNA activates cytoplasmic DNA-sensing pathways… 
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Highly Cited
2015
Highly Cited
2015
Innate immune pattern recognition receptors sense nucleic acids from microbes and orchestrate cytokine production to resolve… 
Highly Cited
2013
Highly Cited
2013
Internal ribosome entry site (IRES) elements found in the 5′ untranslated region of mRNAs enable translation initiation in a cap… 
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Review
2003
Review
2003
Deoxyribonuclease (DNase) II, which was discovered more than 50 years ago, is a mammalian endonuclease that functions optimally… 
Highly Cited
2003
Highly Cited
2003
We have proposed a cancer treatment modality based on poliovirus chimeras replicating under the translational control of an… 
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Highly Cited
1998
Highly Cited
1998
ABSTRACT The most widely recognized biochemical change associated with the majority of apoptotic systems is the degradation of… 
Highly Cited
1998
Highly Cited
1998
We have cloned and sequenced novel cDNAs that encode human and murine DNase II, the acidic deoxyribonuclease. Sequence analysis… 
1998
1998
Porcine spleen DNase II, a lysosomal acid hydrolase, is a noncovalently linked α·β heterodimer (Liao, T.-H. (1985) J. Biol. Chem… 
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Highly Cited
1986
Highly Cited
1986
We analyzed the uptake and intracellular distribution of 125I-labeled epidermal growth factor, nerve growth factor, and platelet… 
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Highly Cited
1979
Highly Cited
1979
Detailed procedures are presented which allow reproducible preparation of T4 gene 32 protein, a helix-destabilizing protein… 
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