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Type 2 Autoimmune Lymphoproliferative Syndrome

Known as: ALPS-CASP10, Autoimmune Lymphoproliferative Syndrome-CASP10 variant, Type 2 ALPS 
A rare, primary immunodeficiency with an autosomal dominant pattern of inheritance but incomplete penetrance. It is caused by a mutation in the… 
National Institutes of Health

Related topics

Related topics

10 relations
AnemiaAtypical lymphocyteAutoimmune DiseasesHodgkin Disease

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Clinical Spectrum of Autoimmune Lymphoproliferative Syndrome Associated with Caspase10 Mutations (ALPS-CASP10)
Autoimmune lymphoproliferative syndrome (ALPS) is a rare disorder of the immune system due to defective Fas-mediated apoptosis… 
Highly Cited
2010
Highly Cited
2010
Association of the Variants CASP8 D302H and CASP10 V410I with Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
Background: The genes caspase-8 (CASP8) and caspase-10 (CASP10) functionally cooperate and play a key role in the initiation of… 
Highly Cited
2006
Highly Cited
2006
Association of the CASP10 V410I variant with reduced familial breast cancer risk and interaction with the CASP8 D302H variant.
Dysregulation of apoptosis plays a crucial role in carcinogenesis. As part of death receptor- and mitochondrion-mediated… 
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