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Type-1 Polarized Dendritic Cell-induced Antigen-specific Autologous Cytotoxic T Lymphocytes
Known as:
Autologous DC1-CTL
, DC1-induced Antigen-specific Autologous CTLs
, Type-1 Polarized DC-induced Antigen-specific Autologous CTLs
A preparation of autologous cytotoxic T-lymphocytes (CTL), specifically reactive to melanoma-associated antigen 3 (MAGE-3), MAGE-4, survivin, human…
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National Institutes of Health
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Related topics
Related topics
4 relations
Antigen Sensitization
Cytotoxic T-Lymphocytes
T-Cell Activation
immunopotentiation
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Inactivation of the PI3K p110δ breaks regulatory T cell-mediated immune tolerance to cancer
K. Ali
,
Dalya R. Soond
,
+11 authors
B. Vanhaesebroeck
Nature
2014
Corpus ID: 4452677
Inhibitors against the p110δ isoform of phosphoinositide-3-OH kinase (PI(3)K) have shown remarkable therapeutic efficacy in some…
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Highly Cited
2008
Highly Cited
2008
Inhibition of STAT3 Promotes the Efficacy of Adoptive Transfer Therapy Using Type-1 CTLs by Modulation of the Immunological Microenvironment in a Murine Intracranial Glioma1
M. Fujita
,
Xinmei Zhu
,
+4 authors
H. Okada
Journal of Immunology
2008
Corpus ID: 32563914
A variety of cancers, including malignant gliomas, show aberrant activation of STAT3, which plays a pivotal role in negative…
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Highly Cited
2002
Highly Cited
2002
Identification of HLA-A2–restricted CD8+ Cytotoxic T Cell Responses in Primary Biliary Cirrhosis
H. Kita
,
Zhe-Xiong Lian
,
+7 authors
M. Gershwin
Journal of Experimental Medicine
2002
Corpus ID: 86840564
Primary biliary cirrhosis (PBC) is characterized by an intense biliary inflammatory CD4+ and CD8+ T cell response. Very limited…
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Highly Cited
2001
Highly Cited
2001
The epithelial tumor antigen MUC1 is expressed in hematological malignancies and is recognized by MUC1-specific cytotoxic T-lymphocytes.
P. Brossart
,
A. Schneider
,
+6 authors
W. Brugger
Cancer Research
2001
Corpus ID: 820609
The epithelial mucin MUC1 is overexpressed on the cell surface of many epithelial malignancies as well as on some B-cell…
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2001
2001
MUC1-specific cytotoxic T lymphocytes eradicate tumors when adoptively transferred in vivo.
P. Mukherjee
,
A. R. Ginardi
,
T. Tinder
,
C. Sterner
,
S. Gendler
Clinical Cancer Research
2001
Corpus ID: 14246255
We have reported previously that MUC1 transgenic mice with spontaneous tumors of the pancreas (designated MET) naturally develop…
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Highly Cited
1999
Highly Cited
1999
Feasibility of immunotherapy of relapsed leukemia with ex vivo-generated cytotoxic T lymphocytes specific for hematopoietic system-restricted minor histocompatibility antigens.
T. Mutis
,
R. Verdijk
,
E. Schrama
,
B. Esendam
,
A. Brand
,
E. Goulmy
Blood
1999
Corpus ID: 23532059
Allogeneic bone marrow transplantation (BMT) is a common treatment of hematologic malignancies. Recurrence of the underlying…
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Highly Cited
1999
Highly Cited
1999
Dendritic Cells Infiltrating Tumors Cotransduced with Granulocyte/Macrophage Colony-Stimulating Factor (Gm-Csf) and Cd40 Ligand Genes Take up and Present Endogenous Tumor-Associated Antigens, and…
C. Chiodoni
,
P. Paglia
,
A. Stoppacciaro
,
M. Rodolfo
,
M. Parenza
,
M. Colombo
Journal of Experimental Medicine
1999
Corpus ID: 10328594
We transduced BALB/c-derived C-26 colon carcinoma cells with granulocyte/macrophage colony-stimulating factor (GM-CSF) and CD40…
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Highly Cited
1999
Highly Cited
1999
A Human Minor Histocompatibility Antigen Specific for B Cell Acute Lymphoblastic Leukemia
H. Dolstra
,
H. Fredrix
,
+7 authors
E. van de Wiel-van Kemenade
Journal of Experimental Medicine
1999
Corpus ID: 405080
Human minor histocompatibility antigens (mHags) play an important role in the induction of cytotoxic T lymphocyte (CTL…
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Highly Cited
1998
Highly Cited
1998
High Frequency of Skin-homing Melanocyte-specific Cytotoxic T Lymphocytes in Autoimmune Vitiligo
G. Ogg
,
P. Rod Dunbar
,
P. Romero
,
Ji-Li Chen
,
V. Cerundolo
Journal of Experimental Medicine
1998
Corpus ID: 16024558
Vitiligo is an autoimmune condition characterized by loss of epidermal melanocytes. Using tetrameric complexes of human…
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Highly Cited
1998
Highly Cited
1998
Anti‐MUC1 class I restricted CTLs in metastatic breast cancer patients immunized with a synthetic MUC1 peptide
M. Reddish
,
G. Maclean
,
+4 authors
B. Longenecker
International Journal of Cancer
1998
Corpus ID: 23038004
Sixteen metastatic breast cancer patients were immunized with a low dose (5 μg) of a 16 amino acid MUC1 peptide (GVTSAPDTRPAPGSTA…
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