Two-hybrid screening

Known as: E. coli two hybrid testing, Saccharomyces cerevisiae two-hybrid analysis, E. coli two hybrid test 
Two-hybrid screening (also known as yeast two-hybrid system or Y2H) is a molecular biology technique used to discover protein–protein interactions… (More)
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Highly Cited
2013
Highly Cited
2013
Circulating tumor cells (CTC) released into blood from primary cancers and metastases reflect the current status of tumor… (More)
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Highly Cited
2006
Highly Cited
2006
Relative quantification methods have dominated the quantitative proteomics field. There is a need, however, to conduct absolute… (More)
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Highly Cited
2006
Highly Cited
2006
Protein interactions are crucial components of all cellular processes. Recently, high-throughput methods have been developed to… (More)
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Highly Cited
2005
Highly Cited
2005
Yeast two-hybrid screens are an important method for mapping pairwise physical interactions between proteins. The fraction of… (More)
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Highly Cited
2003
Highly Cited
2003
The underlying mechanism of circadian rhythmicity appears to be conserved among organisms, and is based on negative… (More)
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Highly Cited
2001
Highly Cited
2001
In this paper we present two hybrid Particle Swarm Optimisers combining the idea of the particle swarm with concepts from… (More)
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Highly Cited
1997
Highly Cited
1997
PLANKTONIC bacteria are a fundamental component of the organic carbon cycle in aquatic systems1. Organic carbon consumption by… (More)
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Highly Cited
1996
Highly Cited
1996
THE cytoplasmic proteins β-catenin of vertebrates and armadillo of Drosophila have two functions: they link the cadherin cell… (More)
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Highly Cited
1984
Highly Cited
1984
A temperature-sensitive DNA topoisomerase II mutant of the yeast Saccharomyces cerevisiae has been identified. Genetic analysis… (More)
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Highly Cited
1975
Highly Cited
1975
About 300 carcinogens and non-carcinogens of a wide variety of chemical types have been tested for mutagenicity in the simple… (More)
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