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Two-Dimensional Difference Gel Electrophoresis

Known as: 2 Dimensional Difference Gel Electrophoresis, 2-Dimensional Difference Gel Electrophoresis, 2D-DIGE 
Methods of comparing two or more samples on the same two-dimensional gel electrophoresis gel.
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
BackgroundNanometer silicon dioxide (nano-SiO2) has a wide variety of applications in material sciences, engineering and medicine… 
Highly Cited
2007
Highly Cited
2007
Proteome data combined with histopathological information provides important, novel clues for understanding cancer biology and… 
Highly Cited
2007
Highly Cited
2007
Understanding the molecular background of breast cancer biology is critical in developing new biomarkers for earlier diagnosis… 
Highly Cited
2006
Highly Cited
2006
To investigate aberrant plasma proteins in lung cancer, we compared the proteomic profiles of serum from five lung cancer… 
Highly Cited
2006
Highly Cited
2006
Quantitative proteomics is the workhorse of the modern proteomics initiative. The gel-based and MuDPIT approaches have… 
Highly Cited
2005
Highly Cited
2005
MOTIVATION The DeCyder software (GE Healthcare) is the current state-of-the-art commercial product for the analysis of two… 
Highly Cited
2004
Highly Cited
2004
Two‐dimensional difference gel electrophoresis (DIGE) is a tool for measuring changes in protein expression between samples… 
Highly Cited
2003
Highly Cited
2003
The comparison of two‐dimensional (2‐D) gel images from different samples is an established method used to study differences in… 
Highly Cited
2003
Highly Cited
2003
Two‐dimensional difference gel electrophoresis (2‐D DIGE) enables an increased confidence in detection of protein differences… 
Highly Cited
2002
Highly Cited
2002
Overdose of acetaminophen (APAP) causes severe centrilobular hepatic necrosis in humans and experimental animals. Here, to…