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Tumor Suppressor Gene Inactivation Process
Tumor Suppressor Gene Inactivation
Any DNA sequence alteration process occurring in a tumor suppressor gene, resulting in loss of function of the gene product, and predisposing the…
National Institutes of Health
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INI1-Deficient Tumors: Diagnostic Features and Molecular Genetics
The American journal of surgical pathology
Corpus ID: 28623311
Significant progress has been made in understanding the molecular genetic alterations involved in sarcomagenesis. Cytogenetic and…
Somatic alterations in the human cancer genome.
Corpus ID: 19821575
Most human malignancies are caused by somatic alterations within the cancer genome, leading to oncogene activation or tumor…
Genetic alterations in head and neck squamous cell carcinomas.
Brazilian journal of medical and biological…
Corpus ID: 29077776
The genetic alterations observed in head and neck cancer are mainly due to oncogene activation (gain of function mutations) and…
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