Tumor Antigen-specific Antibody

Known as: Anti-Tumor Antibody, Anti-Tumor Antigen Antibody, Tumor-Specific Antibody 
Any antibody that recognizes antigens that are overexpressed by, mutated in, or predominantly expressed by tumors compared with normal tissues.
National Institutes of Health

Papers overview

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2011
2011
Antibody-dependent cell cytotoxicity (ADCC) plays a critical role in monoclonal antibody (mAb)-mediated cancer therapy. ADCC… (More)
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2007
2007
IFN-alpha, a cytokine crucial for the innate immune response, also demonstrates antitumor activity. However, use of IFN-alpha as… (More)
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2007
2007
Recombinant immunotoxins are chimeric proteins composed of the Fv portion of a tumor-specific antibody fused to a toxin. SS1P… (More)
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Highly Cited
2006
Highly Cited
2006
Consisting of a silica core surrounded by a thin gold shell, nanoshells possess an optical tunability that spans the visible to… (More)
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2006
2006
FVB/N mice transgenic for nontransforming rat neu develop spontaneous breast cancers that are neu positive and estrogen receptor… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE Presence of intratumoral T-cell infiltration has been linked to improved survival in ovarian cancer patients. We… (More)
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2004
2004
The identification of tumor-specific cell surface antigens is a critical step toward the development of targeted therapeutics for… (More)
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1999
1999
The suppression and eradication of primary tumors and distant metastases is a major goal of alternative treatment strategies for… (More)
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1998
1998
The antitumor specificity of T cells can be induced by gene transfer using a recently developed therapeutic approach (T body). In… (More)
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1986
1986
Heteroaggregates containing anti-T3 cross-linked to anti-target cell antibodies have been shown to cause human T cells to lyse… (More)
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