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Tubulin Beta-3 Chain

Known as: Tuj-1 Antigen, Tubulin Beta-III, Tubulin Beta-4 Chain 
Tubulin beta-3 chain (450 aa, ~50 kDa) is encoded by the human TUBB3 gene. This protein is involved in both axonal guidance and microtubule structure… 
National Institutes of Health

Related topics

Related topics

11 relations
Cell MovementCytokinesisCytoskeletal GeneCytoskeleton

Papers overview

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2016
2016
Expression and clinical significance of ERCC1, TUBB3 and TOP2A mRNA in nephroblastoma
2014
2014
Molecular profiling of 6,892 colorectal cancer patients to identify potential treatment options.
3637 Background: Colorectal cancer (CRC) especially with KRAS/BRAF mutation (MT) is aggressive and has limited treatment options… 
2014
2014
Expression and clinical significance of TS and TUBB3 in gastric cancer tissues
OBJECTIVE:To observe the expression of thymidylate synthase(TS)andβⅢ-tubulin(TUBB3)in gastric cancer tissues and find the… 
2013
2013
TUBB3/STMN1基因表达与非小细胞肺癌EGFR通路的相关性
背景与目的 已有研究表明分子标志物在指导肺癌个体化治疗中起着重要作用。本研究旨在探讨非小细胞肺癌（non-small cell lung cancer, NSCLC）抗微管类药物靶点TUBB3（tubulin, beta 3 class Ⅲ)/STMN1… 
2013
2013
Abstract 1957: MiR-200c can mediate either poor or good outcome in ovarian cancer depending on HuR localization in the cell.
Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC MicroRNAs (miRNAs) in solid malignancies can behave… 
2012
2012
Therapeutic Discovery Restoration of miR-200 c to Ovarian Cancer Reduces Tumor Burden and Increases Sensitivity to Paclitaxel
A therapeutic intervention that could decrease tumor burden and increase sensitivity to chemotherapy would have a significant… 
2011
2011
Predictive Biomarkers and Personalized Medicine Class III b-Tubulin in Advanced NSCLC of Adenocarcinoma Subtype Predicts Superior Outcome in a Randomized Trial
Purpose: Platinum-based doublets are the cornerstone of treatment in advanced non–small-cell lung cancer (NSCLC) and often… 
2008
2008
Prognostic value of class III b-tubulin (TUBB3) in operable non-small cell lung cancer (NSCLC) and predictive value for adjuvant cisplatin-based chemotherapy (CT): A validation study on three…
7506 Background: The IALT and JBR.10 randomized trials both demonstrated the survival advantage of adjuvant platinum-based CT for…