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Tripelennamine

Known as: Tripelennamine [Chemical/Ingredient], Tripelennamina, 1,2-Ethanediamine, N,N-dimethyl-N'-(phenylmethyl)-N'-2-pyridinyl- 
A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat ASTHMA; HAY FEVER; URTICARIA; and… Expand
National Institutes of Health

Related topics

Related topics

27 relations

Broader (3)

AminopyrineAnti-Allergic AgentsHistamine H1 Antagonists
Angle Closure GlaucomaBladder neck obstructionDrug AllergyHistamine H1 Receptor Antagonists [MoA]
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Narrower (4)

Asid Bonz Brand of Tripelennamine HydrochlorideAzaronHistantinPyribenzamine

Papers overview

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Highly Cited
2009
Highly Cited
2009
Ruthenium-catalyzed N-alkylation of amines and sulfonamides using borrowing hydrogen methodology.
The alkylation of amines by alcohols has been achieved using 0.5 mol % [Ru(p-cymene)Cl(2)](2) with the bidentate phosphines dppf… Expand
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2006
2006
Potentiation of pentazocine conditioned place preference by tripelennamine in rats
The effects of tripelennamine on place preference conditioning in rats with pentazocine were investigated. Pentazocine at a dose… Expand
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Highly Cited
1995
Highly Cited
1995
Expressed human UGT1.4 protein catalyzes the formation of quaternary ammonium-linked glucuronides.
In humans, the metabolism of a number of tertiary amine-containing pharmacological agents to quaternary ammonium-linked… Expand
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1985
1985
Outbreak of endocarditis caused by Pseudomonas aeruginosa serotype O11 among pentazocine and tripelennamine abusers in Chicago.
At Cook County Hospital (Chicago), before 1977, the incidence of endocarditis caused by Pseudomonas aeruginosa was one or two… Expand
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1985
1985
Selective survival in pentazocine and tripelennamine of Pseudomonas aeruginosa serotype O11 from drug addicts.
The growth of Pseudomonas aeruginosa, particularly serotype O11, in pentazocine and tripelennamine ("T's and Blues") was… Expand
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Highly Cited
1980
Highly Cited
1980
Zero order drug delivery from double-layered porous films: release rate profiles from ethyl cellulose, hydroxypropyl cellulose and polyethylene glycol mixtures.
Laminated double-layered films comprising a drug-containing and drug-free layer were prepared using tripelennamine, barbitone… Expand
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1980
1980
T's and blues. Abuse of pentazocine and tripelennamine.
Pentazocine, long an abused drug among the medical community, has become popular among street addicts. The tablet form of… Expand
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1980
1980
Pentazocine and tripelennamine: a drug abuse epidemic?
The change in illicit drug use from 1975 to 1978 was studied in Chicago veterans. Barbiturates and amphetamine use has decreased… Expand
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1976
1976
Metabolism of tripelennamine in man.
Four polar metabolites were isolated from the urine of human subjects orally treated with tripelennamine, and their structures… Expand
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Highly Cited
1974
Highly Cited
1974
Effects of hemorrhage on regional blood flow distribution in dogs and primates.
The effects of hemorrhage on arterial pressure, blood flows, and resistances in the coronary, mesenteric, renal, and iliac beds… Expand
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