Trifluridine

Known as: Trifluoromethyldeoxyuridine, 5 Trifluoromethyl 2' deoxyuridine, Thymidine, alpha,alpha,alpha-trifluoro- 
A fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1962-2017
010203019622017

Papers overview

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2011
2011
TAS-102 is an oral anticancer drug composed of trifluorothymidine (TFT) and TPI (an inhibitor of thymidine phosphorylase that… (More)
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2010
2010
Trifluorothymidine (TFT) is part of the oral drug formulation TAS-102. Both 5-fluorouracil (5-FU) and TFT can inhibit thymidylate… (More)
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2005
2005
Trifluorothymidine (FTD) is a thymidine analog that exhibits an antitumor activity through its inhibition of thymidylate synthase… (More)
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1999
1999
PURPOSE To determine the relative antiviral inhibitory activity of topical 1% and 0.5% cidofovir, topical trifluridine (Viroptic… (More)
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1998
1998
OBJECTIVE To compare trifluridine eyedrops, cidofovir eyedrops, and penciclovir ophthalmic ointment for the treatment of herpes… (More)
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1989
1989
In vitro activities of 9-[( 2-hydroxyethoxy] methyl) guanine (acyclovir), (E)-5-(2-bromovinyl)-2'deoxyuridine, 9-beta-D… (More)
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1983
1983
Prolonged topical trifluridine treatment of herpes simplex keratitis in three elderly patients produced slightly raised… (More)
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1982
1982
Two compounds, bromovinyldeoxyuridine ([E]-5-[2-bromovinyl]-2'-deoxyuridine) and trifluridine (5-trifluoromethyl-2' deoxyuridine… (More)
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1979
1979
We studied intraocular penetration of topically applied trifluridine in five patients with herpetic keratitis undergoing… (More)
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1964
1964
5-Trifluoromethyl-2'-deoxyuridine (F(3)TDR) has potent therapeutic antiviral activity in herpes simplex infection of the rabbit… (More)
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