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Trichloroepoxypropane
Known as:
Oxirane, (trichloromethyl)-
, Trichloropropane Oxide
, Trichloroepoxypropane [Chemical/Ingredient]
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A potent epoxide hydrase and aryl hydrocarbon hydroxylase inhibitor. It enhances the tumor-initiating ability of certain carcinogens.
National Institutes of Health
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Related topics
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8 relations
Broader (1)
Enzyme Inhibitors
In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Embryotoxicity and teratogenicity of styrene and styrene oxide on chick embryos enhanced by trichloropropylene oxide.
J. T. Kankaanpää
,
K. Hemminki
,
H. Vainio
Acta Pharmacologica et Toxicologica
2009
Corpus ID: 6305860
The effects of TCPO (trichloropropylene oxide) on the embryotoxicity and teratogenicity of styrene and styrene oxide and chick…
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2009
2009
Effects of various in vitro--inhibitors of benzo(a)pyrene metabolism in isolated rat lung perfusion.
K. Vähäkangas
,
K. Nevasaari
,
O. Pelkonen
,
N. Kärki
Acta Pharmacologica et Toxicologica
2009
Corpus ID: 7397174
Various in vitro-inhibitors were added with 3H-benzo(a)pyrene (BP) into the perfusion fluids in isolated rat lung perfusions to…
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2006
2006
Benzo(fl)pyrene Metabolism by Murine Spleen Microsomes1
T. Kawabata
,
K. White
2006
Corpus ID: 14881297
The immunosuppressive actions of benzo(a)pyrene have been proposed to be mediated by reactive metabolites rather than the parent…
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2004
2004
Dose-dependent effect of trichloropropene oxide on benzo[a]pyrene carcinogenesis
M. Kodama
,
Y. Ioki
,
C. Nagata
Journal of Cancer Research and Clinical Oncology
2004
Corpus ID: 2590261
SummaryThe epoxide hydratase inhibitor, 1,1,1-trichloro-2,3-propene oxide (TCPO) in combination with benzo[a]pyrene (B[a]P) was…
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1988
1988
[Comparative characteristics of microsomal epoxide hydrolase in the rat liver and small intestine mucosa].
L. Kravchenko
,
E. E. Kuz'mina
,
V. Sobolev
Voprosy medicinskoj himii
1988
Corpus ID: 13046695
Activity of epoxide hydrolase was studied in microsomes of rat liver and small intestinal mucosa with styrene oxide as substrate…
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1981
1981
Mechanism of the toxic action of benz(a)pyrene and its derivatives in tissue culture
I. Khitrovo
,
G. Belitskii
,
V. Koblyakov
Bulletin of experimental biology and medicine
1981
Corpus ID: 5821079
Commercial preparations of BP (from Fluka, Switzerland) and of trichloropropene oxide (TCPO) (from Aldrich) were used in the…
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1980
1980
The epoxide-diol pathway in the metabolism of vinylbital in rat and man.
N. Vermeulen
,
B. H. Bakker
,
D. Eylers
,
D. Breimer
Xenobiotica; the fate of foreign compounds in…
1980
Corpus ID: 28063003
1. In urine of rats given vinylbital (5-vinyl-5-(1'-methylbutyl)barbituric acid) i.p., unchanged vinylbital and its devinylated…
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1979
1979
Effect of trichloropropene oxide and benzoflavone on polycyclic hydrocarbon carcinogenesis in C3H/He and DBA/2 mice.
M. Watanabe
,
K. Watanabe
,
H. Sato
Gan
1979
Corpus ID: 39380956
Effect of 1,1,1-trichloropropene 2,3-oxide and 7,8-benzoflavone on benzo[a]-pyrene and 3-methylcholanthrene carcinogenesis in the…
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1979
1979
Effect of Trichloropropene Oxide and Benzoflavone on Polycyclic Hydrocarbon Carcinogenesis in C3H/He and DBA/2 Mice
渡辺 民朗
,
渡辺 紀予子
,
佐藤 春郎
1979
Corpus ID: 93968088
1976
1976
The direct spectrophotometric observation of benzo(a)pyrene phenol formation by liver microsomes.
R. Prough
,
V. Patrizi
,
R. Estabrook
Cancer Research
1976
Corpus ID: 9363102
Optical spectral repetitive scan analysis during the oxidative metabolism of benzo(a)pyrene by liver microsomal suspensions…
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