Skip to search formSkip to main contentSkip to account menu

Transthyretin Antisense Oligonucleotide ISIS-TTR Rx

Known as: ISIS-TTR Rx, ISIS-TTRRx, TTR ASO ISIS-TTR Rx 
An antisense oligonucleotide (ASO) targeting transthyretin (TTR), which has potential use in the treatment of TTR amyloidosis (ATTR). Upon… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Development of ISIS-TTR Rx for Transthyretin Familial Amyloid Polyneuropathy (TTR-FAP) (S34.009)
Objective: To treat Transthyretin Familial Amyloid Polyneuropathy (TTR-FAP) patients via reduction of mutated and wild-type TTR… 
2014
2014
Results of a Phase 2 Open-Label Study of ISIS-SMNRx in Patients with Infantile (Type 1) Spinal Muscular Atrophy (S6.003)
Objective: This study was conducted to evaluate the safety, tolerability, pharmacokinetics, and clinical efficacy of multiple… 
2014
2014
G.O.18 Results of a phase 2 study of ISIS-SMNRx in children with spinal muscular atrophy
2014
2014
G.O.17 Results of a phase 2 open-label study of ISIS-SMNRx in patients with infantile (Type 1) spinal muscular atrophy
Review
2013
Review
2013
A 180 MEV INJECTION UPGRADE DESIGN FOR THE ISIS SYNCHROTRON
ISIS is the spallation neutron source at the Rutherford Appleton Laboratory in the UK. Obsolescence and reliability issues are… 
2012
2012
6 Biomechanical Analysis of Restored Teeth with Cast Intra-Radicular Retainer with and Without Ferrule Isis Andréa
The intra-radicular post is used to provide retention to a core, but would also have the function of distributing the functional… 
2008
2008
The Effects of Sponge Haliclona sp and Gorgonian Isis hippuris Combination Extract on Histopathological Feature of Swiss Mice Liver
Backgrounds: Sponge Haliclona sp and Gorgonian Isis hippuris are marine organisms whose extracts are potential for anticancer… 
2007
2007
Spectral Coherence Interferometry (SCI) for fast and rugged industrial applications
Summary form only given. Standard optical coherence tomography (OCT) has been proven to provide surface and general 3D metrology… 
1996
1996
Isis prerromana, Isis romana
1972
1972
JULIAN-HELIOS SARAPIS UND HELENA-ISIS. MIT 31 ABBILDUNGEN
A HANAREB, A ENVIRON 70 KM DE L'ANTIQUE SUFETULA, LA TUNISIENNE SBEITLA, A ETE TROUVEE UNE LAMPE DE TERRE CUITE D'EPOQUE ROMAINE… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)