Transplantation Tolerance

Known as: Tolerance, Transplantation 
An induced state of non-reactivity to grafted tissue from a donor organism that would ordinarily trigger a cell-mediated or humoral immune response.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
One of the main unresolved questions in solid organ transplantation is how to establish indefinite graft survival that is free… (More)
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Highly Cited
2006
Highly Cited
2006
In many experimental models, heart, pancreas and kidney allografts are accepted long-term following costimulation-targeting… (More)
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Highly Cited
2004
Highly Cited
2004
Despite the ease of inhibiting immune responses by blockade of T-cell costimulation in naive rodent models, it is difficult to… (More)
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Highly Cited
2003
Highly Cited
2003
Although T helper (TH) cell–mediated immunity is required to effectively eliminate pathogens, unrestrained TH activity also… (More)
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Highly Cited
2001
Highly Cited
2001
1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, and mycophenolate mofetil, a selective inhibitor of T and B cell… (More)
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Highly Cited
2000
Highly Cited
2000
Allogeneic bone marrow transplantation (in immunocompetent adults) has always required cytoreductive treatment of recipients with… (More)
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Highly Cited
1994
Highly Cited
1994
The rejection of the transplanted allograft is dependent on T cell activation, which requires T cell receptor engagement by… (More)
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Highly Cited
1993
Highly Cited
1993
The maintenance of transplantation tolerance induced in adult mice after short-term treatment with nonlytic monoclonal antibodies… (More)
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Highly Cited
1989
Highly Cited
1989
The use of allogeneic bone marrow transplantation as a means of inducing donor-specific tolerance across MHC barriers could… (More)
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Highly Cited
1977
Highly Cited
1977
BALB/c mice were treated with fractionated high dose (3,400 rads) total lymphoid irradiation (TLI), and given semiallogeneic… (More)
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