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Transplacental Carcinogenesis

Studies of the mechanisms of induction of cancer in an individual by in utero exposure to a carcinogen.
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Relevance of experimental models for investigation of genotoxicity induced by antiretroviral therapy during human pregnancy.
  • O. Olivero
  • Mutation research
  • 2008
  • Corpus ID: 13771012
2007
2007
Transplacental carcinogenicity of 3′‐azido‐3′‐deoxythymidine in B6C3F1 mice and F344 rats
The prophylactic use of zidovudine (3′‐azido‐3′‐deoxythymidine, AZT) during pregnancy greatly reduces transmission of HIV‐1 from… 
2003
2003
Effect of fundal pressure on maternal to fetal microtransfusion at the time of cesarean delivery
Aim:  To determine if fundal pressure at the time of cesarean delivery increases the amount of transplacental microtransfusion… 
Highly Cited
2000
Highly Cited
2000
Oxidative DNA damage in fetal tissues after transplacental exposure to 3'-azido-3'-deoxythymidine (AZT).
The nucleoside analogue 3'-azido-3'-deoxythymidine (AZT) has been used successfully to reduce the incidence of transplacental and… 
1995
1995
Fetal mouse susceptibility to transplacental carcinogenesis: differential influence of Ah receptor phenotype on effects of 3-methylcholanthrene, 12-dimethylbenz[a]anthracene, and benzo[a]pyrene.
Genetic backcrosses of C57BL/6 and DBA/2 mice were used to examine the influence of maternal and fetal polymorphisms at the Ahr… 
1989
1989
Maternal-neonatal serum vitamin A concentrations.
Prevention of neonatal vitamin A deficiency is related to the adequacy of maternal vitamin A stores. In this study we… 
Review
1989
Review
1989
Use of the 32P-postlabelling assay to study transplacental carcinogens and transplacental carcinogenesis.
The formation of DNA adducts represents a key step in the postnatal initiation of the carcinogenic process. Little is known as… 
1987
1987
Ethylnitrosourea-induced transplacental carcinogenesis in the mouse: tumor response, DNA binding, and adduct formation.
We have confirmed previous results which suggest that transplacental exposure of fetal mice to carcinogens does not cause an… 
1985
1985
Fetal mouse susceptibility to transplacental lung and liver carcinogenesis by 3-methylcholanthrene: positive correlation with responsiveness to inducers of aromatic hydrocarbon metabolism.
The role of metabolic activation of carcinogens in fetal tissue as a determinant of sensitivity in transplacental carcinogenesis… 
1948
1948
Microscopic observations of the placental barrier in transplacental erythrocytotoxic anemia (erythroblastosis fetalis) and in normal pregnancy.
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