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Translational Medical Research

Known as: Translational Medical Sciences, Sciences, Translational Medical, Medical Sciences, Translational 
The application of discoveries generated by laboratory research and preclinical studies to the development of clinical trials and studies in humans… 
National Institutes of Health

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Educational aspectsKnowledge TranslationNational Center for Advancing Translational Sciences (U.S.)Translational Research

Papers overview

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Review
2015
Review
2015
Expression quantitative trait locus analysis for translational medicine
Expression quantitative trait locus analysis has emerged as an important component of efforts to understand how genetic… 
Review
2015
Review
2015
Virus-based nanomaterials as positron emission tomography and magnetic resonance contrast agents: from technology development to translational medicine.
Viruses have recently emerged as ideal protein scaffolds for a new class of contrast agents that can be used in medical imaging… 
2015
2015
Pluripotent and Metabolic Features of Two Types of Porcine iPSCs Derived from Defined Mouse and Human ES Cell Culture Conditions
The domestic pig is an excellent animal model for stem cell research and clinical medicine. There is still no suitable culture… 
Highly Cited
2012
Highly Cited
2012
Strengthening the Career Development of Clinical Translational Scientist Trainees: A Consensus Statement of the Clinical Translational Science Award (CTSA) Research Education and Career Development…
The challenges for scholars committed to successful careers in clinical and translational science are increasingly well… 
Review
2012
Review
2012
Translational semantics and infrastructure: another search for the emperor's new clothes?
Review
2011
Review
2011
Can functional magnetic resonance imaging improve success rates in central nervous system drug discovery?
Introduction: The bar for developing new treatments for CNS disease is getting progressively higher and fewer novel mechanisms… 
Review
2009
Review
2009
Pharmacologic Interventions for Stroke: Looking Beyond the Thrombolysis Time Window Into the Penumbra With Biomarkers, Not a Stopwatch
Background and Purpose— The majority of pharmacological agents for stroke were developed based on the assumption that… 
Review
2008
Review
2008
Cognitive endpoints as disease biomarkers: optimizing the congruency of preclinical models to the clinic.
Cognition is a complex set of processes, including attention, learning and memory, that refers to the capacity to encode… 
2006
2006
Imaging biomarkers as surrogate endpoints for drug development
The employment of biomarkers (including imaging biomarkers, especially PET) in drug development has gained increasing attention… 
2005
2005
Application of predictive biosimulation within pharmaceutical clinical development: examples of significance for translational medicine and clinical trial design.
The challenge of accurately predicting human clinical outcome based on preclinical data has led to a high failure rate of… 
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