Transcriptional Activation Domain

A DNA-binding domain binds to a specific DNA sequence and a transcriptional activation domain interacts with the basal transcriptional machinery. An… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2018
0102019862018

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Highly Cited
2013
Highly Cited
2013
Technologies allowing for specific regulation of endogenous genes are valuable for the study of gene functions and have great… (More)
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Highly Cited
2001
Highly Cited
2001
The ability of transcriptional activation domains (TADs) to signal ubiquitin-mediated proteolysis suggests an involvement of the… (More)
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Highly Cited
2001
Highly Cited
2001
Mammals express four highly conserved TEAD/TEF transcription factors that bind the same DNA sequence, but serve different… (More)
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Highly Cited
2000
Highly Cited
2000
Previous studies have shown that upregulation of the orphan steroid receptor Nur77 is required for the apoptosis of immature T… (More)
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Highly Cited
2000
Highly Cited
2000
DNA transcription is initiated by a small regulatory region of transactivators known as the transactivation domain. In contrast… (More)
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Highly Cited
1997
Highly Cited
1997
Heat shock transcription factor 1 (HSF1) is constitutively expressed in mammalian cells and negatively regulated for DNA binding… (More)
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Highly Cited
1997
Highly Cited
1997
Two lines of evidence suggest that the Sry-related gene Sox9 is important for chondrogenesis in mammalian embryos. Sox9 mRNA is… (More)
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Highly Cited
1995
Highly Cited
1995
The ATF-2 transcription factor can mediate adenovirus E1A-inducible transcriptional activation. Deletion analysis has indicated… (More)
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Highly Cited
1993
Highly Cited
1993
The Elk-1 and SRF transcription factors form a ternary complex at the c-fos serum response element (SRE). Growth factor… (More)
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Highly Cited
1991
Highly Cited
1991
Virion protein 16 (VP16) of herpes simplex virus type 1 contains an acidic transcriptional activation domain. Missense mutations… (More)
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