Transcriptional Activation Domain

A DNA-binding domain binds to a specific DNA sequence and a transcriptional activation domain interacts with the basal transcriptional machinery. An… (More)
National Institutes of Health

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1986-2018
0102019862018

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ZNF217 protein, human

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1986-2018
19801990200020102020
Transcriptional Activation Domain
ZNF217 protein, human

Papers overview

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Highly Cited
2013
Highly Cited
2013
Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system
Technologies allowing for specific regulation of endogenous genes are valuable for the study of gene functions and have great… (More)
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Highly Cited
2001
Highly Cited
2001
Regulation of transcriptional activation domain function by ubiquitin.
The ability of transcriptional activation domains (TADs) to signal ubiquitin-mediated proteolysis suggests an involvement of the… (More)
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Highly Cited
2001
Highly Cited
2001
TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm.
Mammals express four highly conserved TEAD/TEF transcription factors that bind the same DNA sequence, but serve different… (More)
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Highly Cited
2000
Highly Cited
2000
ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain.
Previous studies have shown that upregulation of the orphan steroid receptor Nur77 is required for the apoptosis of immature T… (More)
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Highly Cited
2000
Highly Cited
2000
Local structural elements in the mostly unstructured transcriptional activation domain of human p53.
DNA transcription is initiated by a small regulatory region of transactivators known as the transactivation domain. In contrast… (More)
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Highly Cited
1997
Highly Cited
1997
Repression of the heat shock factor 1 transcriptional activation domain is modulated by constitutive phosphorylation.
Heat shock transcription factor 1 (HSF1) is constitutively expressed in mammalian cells and negatively regulated for DNA binding… (More)
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Highly Cited
1997
Highly Cited
1997
SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse.
Two lines of evidence suggest that the Sry-related gene Sox9 is important for chondrogenesis in mammalian embryos. Sox9 mRNA is… (More)
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Highly Cited
1995
Highly Cited
1995
ATF-2 contains a phosphorylation-dependent transcriptional activation domain.
The ATF-2 transcription factor can mediate adenovirus E1A-inducible transcriptional activation. Deletion analysis has indicated… (More)
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Highly Cited
1993
Highly Cited
1993
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain.
The Elk-1 and SRF transcription factors form a ternary complex at the c-fos serum response element (SRE). Growth factor… (More)
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Highly Cited
1991
Highly Cited
1991
Critical structural elements of the VP16 transcriptional activation domain.
Virion protein 16 (VP16) of herpes simplex virus type 1 contains an acidic transcriptional activation domain. Missense mutations… (More)
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