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Transcriptional Activation Domain

A DNA-binding domain binds to a specific DNA sequence and a transcriptional activation domain interacts with the basal transcriptional machinery. An… 
National Institutes of Health

Papers overview

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Review
2006
Review
2006
The recent structure of human replication protein A (RPA) bound to residues 38-58 of tumor suppressor p53 exemplifies several… 
2006
2006
The ESE (epithelium-specific Ets) subfamily of Ets transcription factors plays an important role in regulating gene expression in… 
2003
2003
Abstract Activating transcription factor 2 (ATF2) belongs to the family of basic region leucine zipper (bZIP) proteins that are… 
1998
1998
ABSTRACT The MyoD family of basic helix-loop-helix (bHLH) proteins is required for myogenic determination and differentiation… 
1998
1998
The thyroid transcription factor 1 (TTF-1) is a tissue-specific transcription factor involved in the development of thyroid and… 
1996
1996
VP16 activates transcription by stimulating initiation, and for this function the aromatic residue at position 442 within its… 
1994
1994
Alteration of the TAL1 gene is the most common genetic lesion found in patients with T cell acute lymphoblastic leukemia. TAL1… 
1994
1994
The POU domain activator Oct-2 contains an N-terminal glutamine-rich transcriptional activation domain. An 18-amino-acid segment…